Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023821034> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2023821034 endingPage "190" @default.
- W2023821034 startingPage "184" @default.
- W2023821034 abstract "Background: We designed this study to determine whether a combination of dexmedetomidine and sevoflurane postconditioning provides additive neuroprotection in a rat model of transient global cerebral ischemia. Methods: Forty rats were randomly allocated to 4 groups. Control group (group C, n=10) received no treatment. Dexmedetomidine group (group D, n=10) received dexmedetomidine of 100 μg/kg intraperitoneally 30 minutes before ischemia. Sevoflurane postconditioning group (group P, n=10) underwent 2 sevoflurane inhalations after ischemia. Each inhalation consisted of 5 minutes of 2.5% sevoflurane and a subsequent washout time of 10 minutes. Sevoflurane postconditioning plus dexmedetomidine group (group PD, n=10) received received dexmedetomidine and 2 sevoflurane inhalations 30 minutes before ischemia and after ischemia, respectively. In all the groups, ischemia was induced by a bilateral common carotid artery occlusion plus hemorrhagic hypotension and was maintained for 8 minutes. Histologic outcomes and apoptosis-related proteins were measured 7 days after ischemia in the CA1 area of the rat hippocampus. Results: Groups D, P, and PD contained more viable cells and less apoptotic cells in the hippocampal CA1 area than group C (P<0.01). There was a significant difference in the Bax and Bcl-2 expression between group C and other groups (P<0.05). But the number of viable and apoptotic cells, and the Bax and Bcl-2 expression were not statistically different between group D or P and group PD. Conclusions: A combination of preischemic dexmedetomidine and sevoflurane postconditioning provides no additional neuroprotective benefit over preischemic dexmedetomidine or sevoflurane postconditioning alone." @default.
- W2023821034 created "2016-06-24" @default.
- W2023821034 creator A5008530670 @default.
- W2023821034 creator A5023517463 @default.
- W2023821034 creator A5047323666 @default.
- W2023821034 creator A5060257314 @default.
- W2023821034 creator A5087113157 @default.
- W2023821034 date "2013-04-01" @default.
- W2023821034 modified "2023-09-25" @default.
- W2023821034 title "Postischemic Sevoflurane Offers No Additional Neuroprotective Benefit to Preischemic Dexmedetomidine" @default.
- W2023821034 cites W1561672396 @default.
- W2023821034 cites W181832921 @default.
- W2023821034 cites W1967791587 @default.
- W2023821034 cites W1977020962 @default.
- W2023821034 cites W1993786363 @default.
- W2023821034 cites W2009017153 @default.
- W2023821034 cites W2013864444 @default.
- W2023821034 cites W2016703443 @default.
- W2023821034 cites W2018139629 @default.
- W2023821034 cites W2020702152 @default.
- W2023821034 cites W2027285788 @default.
- W2023821034 cites W2027669973 @default.
- W2023821034 cites W2027969205 @default.
- W2023821034 cites W2032555697 @default.
- W2023821034 cites W2036527325 @default.
- W2023821034 cites W2043732191 @default.
- W2023821034 cites W2061068741 @default.
- W2023821034 cites W2071497357 @default.
- W2023821034 cites W2075296319 @default.
- W2023821034 cites W2075863025 @default.
- W2023821034 cites W2077032807 @default.
- W2023821034 cites W2077268854 @default.
- W2023821034 cites W2082311917 @default.
- W2023821034 cites W2084891501 @default.
- W2023821034 cites W2120657639 @default.
- W2023821034 cites W2132842237 @default.
- W2023821034 doi "https://doi.org/10.1097/ana.0b013e3182764d2a" @default.
- W2023821034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23456031" @default.
- W2023821034 hasPublicationYear "2013" @default.
- W2023821034 type Work @default.
- W2023821034 sameAs 2023821034 @default.
- W2023821034 citedByCount "14" @default.
- W2023821034 countsByYear W20238210342014 @default.
- W2023821034 countsByYear W20238210342015 @default.
- W2023821034 countsByYear W20238210342016 @default.
- W2023821034 countsByYear W20238210342017 @default.
- W2023821034 countsByYear W20238210342018 @default.
- W2023821034 countsByYear W20238210342019 @default.
- W2023821034 countsByYear W20238210342020 @default.
- W2023821034 countsByYear W20238210342021 @default.
- W2023821034 countsByYear W20238210342023 @default.
- W2023821034 crossrefType "journal-article" @default.
- W2023821034 hasAuthorship W2023821034A5008530670 @default.
- W2023821034 hasAuthorship W2023821034A5023517463 @default.
- W2023821034 hasAuthorship W2023821034A5047323666 @default.
- W2023821034 hasAuthorship W2023821034A5060257314 @default.
- W2023821034 hasAuthorship W2023821034A5087113157 @default.
- W2023821034 hasConcept C126322002 @default.
- W2023821034 hasConcept C25498285 @default.
- W2023821034 hasConcept C2776814716 @default.
- W2023821034 hasConcept C2781302539 @default.
- W2023821034 hasConcept C2781453256 @default.
- W2023821034 hasConcept C42219234 @default.
- W2023821034 hasConcept C541997718 @default.
- W2023821034 hasConcept C71924100 @default.
- W2023821034 hasConcept C98274493 @default.
- W2023821034 hasConceptScore W2023821034C126322002 @default.
- W2023821034 hasConceptScore W2023821034C25498285 @default.
- W2023821034 hasConceptScore W2023821034C2776814716 @default.
- W2023821034 hasConceptScore W2023821034C2781302539 @default.
- W2023821034 hasConceptScore W2023821034C2781453256 @default.
- W2023821034 hasConceptScore W2023821034C42219234 @default.
- W2023821034 hasConceptScore W2023821034C541997718 @default.
- W2023821034 hasConceptScore W2023821034C71924100 @default.
- W2023821034 hasConceptScore W2023821034C98274493 @default.
- W2023821034 hasIssue "2" @default.
- W2023821034 hasLocation W20238210341 @default.
- W2023821034 hasLocation W20238210342 @default.
- W2023821034 hasOpenAccess W2023821034 @default.
- W2023821034 hasPrimaryLocation W20238210341 @default.
- W2023821034 hasRelatedWork W1968949916 @default.
- W2023821034 hasRelatedWork W2070043446 @default.
- W2023821034 hasRelatedWork W2165070755 @default.
- W2023821034 hasRelatedWork W2785730883 @default.
- W2023821034 hasRelatedWork W2787658580 @default.
- W2023821034 hasRelatedWork W3029444201 @default.
- W2023821034 hasRelatedWork W3029802733 @default.
- W2023821034 hasRelatedWork W3029926134 @default.
- W2023821034 hasRelatedWork W3030289011 @default.
- W2023821034 hasRelatedWork W3030578804 @default.
- W2023821034 hasVolume "25" @default.
- W2023821034 isParatext "false" @default.
- W2023821034 isRetracted "false" @default.
- W2023821034 magId "2023821034" @default.
- W2023821034 workType "article" @default.