FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023822436> ?p ?o ?g. }

• W2023822436 endingPage "386" @default.
• W2023822436 startingPage "380" @default.
• W2023822436 abstract "1. The present study was designed to determine if endogenous kinins are involved in the regulation of arterial blood pressure and renal function in conscious rats given deoxycorticosterone enantate (DOC, 25 mg kg-1, s.c., weekly) or vehicle for two weeks. 2. The bradykinin B2-receptor antagonist, D-Arg[Hyp3,Thi5,D-Tic7,Oic8]- bradykinin (Hoe 140), at a dose of 300 micrograms kg-1, s.c., blocked the hypotensive effect of 300 ng kg-1 bradykinin i.a., but it did not alter the blood pressure lowering action of 300 ng kg-1 acetylcholine or prostaglandin E2. Inhibition of the response to bradykinin persisted up to 6 h after the administration of Hoe 140. 3. Administration of 300 micrograms kg-1 Hoe 140 s.c. four times a day did not alter mean blood pressure, renal blood flow, or renal function in rats given DOC-vehicle. However, it decreased urinary volume by 70% (from 48.2 +/- 3.8 to 14.3 +/- 3.7 ml 24 h-1, P less than 0.01) and urinary secretion of sodium by 54% (from 1.02 +/- 0.05 to 0.47 +/- 0.16 mmol 24 h-1, P less than 0.01) and potassium by 30% (from 2.93 +/- 0.15 to 2.04 +/- 0.15 mmol 24 h-1, P less than 0.05) in DOC-treated rats. Mean blood pressure, glomerular filtration rate and total renal blood flow remained unchanged. 4. Our results suggest that endogenous kinins play a role in the regulation of renal excretion of water and sodium in the presence of elevated levels of DOC." @default.
• W2023822436 created "2016-06-24" @default.
• W2023822436 creator A5003876992 @default.
• W2023822436 creator A5011359646 @default.
• W2023822436 creator A5030889556 @default.
• W2023822436 creator A5044403990 @default.
• W2023822436 creator A5047431034 @default.
• W2023822436 creator A5050973058 @default.
• W2023822436 creator A5059387383 @default.
• W2023822436 creator A5081922606 @default.
• W2023822436 creator A5087433785 @default.
• W2023822436 date "1992-06-01" @default.
• W2023822436 modified "2023-10-17" @default.
• W2023822436 title "Effects of Hoe 140, a bradykinin B2-receptor antagonist, on renal function in conscious normotensive rats" @default.
• W2023822436 cites W1969088301 @default.
• W2023822436 cites W1971442453 @default.
• W2023822436 cites W1974146850 @default.
• W2023822436 cites W1990711762 @default.
• W2023822436 cites W1995559456 @default.
• W2023822436 cites W2007502554 @default.
• W2023822436 cites W2081489964 @default.
• W2023822436 cites W2103006293 @default.
• W2023822436 cites W2108849150 @default.
• W2023822436 cites W2114830145 @default.
• W2023822436 cites W2115286134 @default.
• W2023822436 cites W2115885172 @default.
• W2023822436 cites W2133328297 @default.
• W2023822436 cites W2143177360 @default.
• W2023822436 cites W2147630274 @default.
• W2023822436 cites W2148172817 @default.
• W2023822436 cites W2163280144 @default.
• W2023822436 cites W2168029143 @default.
• W2023822436 cites W2170801299 @default.
• W2023822436 cites W2237794058 @default.
• W2023822436 cites W2281408921 @default.
• W2023822436 cites W2321681050 @default.
• W2023822436 cites W2414942973 @default.
• W2023822436 cites W2415874194 @default.
• W2023822436 cites W2416890084 @default.
• W2023822436 cites W2440218748 @default.
• W2023822436 cites W2472236895 @default.
• W2023822436 cites W4244444868 @default.
• W2023822436 doi "https://doi.org/10.1111/j.1476-5381.1992.tb14344.x" @default.
• W2023822436 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1907524" @default.
• W2023822436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1327379" @default.
• W2023822436 hasPublicationYear "1992" @default.
• W2023822436 type Work @default.
• W2023822436 sameAs 2023822436 @default.
• W2023822436 citedByCount "43" @default.
• W2023822436 countsByYear W20238224362016 @default.
• W2023822436 countsByYear W20238224362018 @default.
• W2023822436 crossrefType "journal-article" @default.
• W2023822436 hasAuthorship W2023822436A5003876992 @default.
• W2023822436 hasAuthorship W2023822436A5011359646 @default.
• W2023822436 hasAuthorship W2023822436A5030889556 @default.
• W2023822436 hasAuthorship W2023822436A5044403990 @default.
• W2023822436 hasAuthorship W2023822436A5047431034 @default.
• W2023822436 hasAuthorship W2023822436A5050973058 @default.
• W2023822436 hasAuthorship W2023822436A5059387383 @default.
• W2023822436 hasAuthorship W2023822436A5081922606 @default.
• W2023822436 hasAuthorship W2023822436A5087433785 @default.
• W2023822436 hasBestOaLocation W20238224361 @default.
• W2023822436 hasConcept C10146269 @default.
• W2023822436 hasConcept C126322002 @default.
• W2023822436 hasConcept C134018914 @default.
• W2023822436 hasConcept C142225936 @default.
• W2023822436 hasConcept C153939273 @default.
• W2023822436 hasConcept C159641895 @default.
• W2023822436 hasConcept C170493617 @default.
• W2023822436 hasConcept C185592680 @default.
• W2023822436 hasConcept C2776885963 @default.
• W2023822436 hasConcept C2778122271 @default.
• W2023822436 hasConcept C2779591629 @default.
• W2023822436 hasConcept C2780091579 @default.
• W2023822436 hasConcept C2781073237 @default.
• W2023822436 hasConcept C71924100 @default.
• W2023822436 hasConcept C84393581 @default.
• W2023822436 hasConceptScore W2023822436C10146269 @default.
• W2023822436 hasConceptScore W2023822436C126322002 @default.
• W2023822436 hasConceptScore W2023822436C134018914 @default.
• W2023822436 hasConceptScore W2023822436C142225936 @default.
• W2023822436 hasConceptScore W2023822436C153939273 @default.
• W2023822436 hasConceptScore W2023822436C159641895 @default.
• W2023822436 hasConceptScore W2023822436C170493617 @default.
• W2023822436 hasConceptScore W2023822436C185592680 @default.
• W2023822436 hasConceptScore W2023822436C2776885963 @default.
• W2023822436 hasConceptScore W2023822436C2778122271 @default.
• W2023822436 hasConceptScore W2023822436C2779591629 @default.
• W2023822436 hasConceptScore W2023822436C2780091579 @default.
• W2023822436 hasConceptScore W2023822436C2781073237 @default.
• W2023822436 hasConceptScore W2023822436C71924100 @default.
• W2023822436 hasConceptScore W2023822436C84393581 @default.
• W2023822436 hasIssue "2" @default.
• W2023822436 hasLocation W20238224361 @default.
• W2023822436 hasLocation W20238224362 @default.
• W2023822436 hasLocation W20238224363 @default.
• W2023822436 hasLocation W20238224364 @default.
• W2023822436 hasOpenAccess W2023822436 @default.

• next