Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023826034> ?p ?o ?g. }
- W2023826034 endingPage "115" @default.
- W2023826034 startingPage "109" @default.
- W2023826034 abstract "Ephrin-A1 and its primary receptor, EphA2, are involved in numerous physiological processes and have been intensely studied for their roles in malignancy. Ephrin–Eph signalling is complex on its own and is also cell-type dependent, making elucidation of the exact role of ephrin-A1 in neoplasia challenging. Multiple oncogenic signalling pathways, such as MAP/ERK and PI3K are affected by ephrin-A1, and in some cases evidence suggests the promotion of a specific pathway in one cell or cancer type and inhibition of the same pathway in another type of cell or cancer. Ephrin-A1 also plays an integral role in angiogenesis and tumor neovascularization. Until recently, studies investigating ephrins focused on the ligands as GPI-anchored proteins that required membrane anchoring or artificial clustering for Eph receptor activation. However, recent studies have demonstrated a functional role for soluble, monomeric ephrin-A1. This review will focus on various forms of ephrin-A1-specific signalling in human malignancy." @default.
- W2023826034 created "2016-06-24" @default.
- W2023826034 creator A5058075606 @default.
- W2023826034 creator A5078092333 @default.
- W2023826034 date "2012-02-01" @default.
- W2023826034 modified "2023-10-16" @default.
- W2023826034 title "Ephs and ephrins in cancer: Ephrin-A1 signalling" @default.
- W2023826034 cites W1573055043 @default.
- W2023826034 cites W1597741096 @default.
- W2023826034 cites W1599775179 @default.
- W2023826034 cites W1964166386 @default.
- W2023826034 cites W1965680643 @default.
- W2023826034 cites W1967628309 @default.
- W2023826034 cites W1967720639 @default.
- W2023826034 cites W1969417879 @default.
- W2023826034 cites W1970537259 @default.
- W2023826034 cites W1976310806 @default.
- W2023826034 cites W1981710976 @default.
- W2023826034 cites W1986920157 @default.
- W2023826034 cites W1992187858 @default.
- W2023826034 cites W1994137567 @default.
- W2023826034 cites W1994760983 @default.
- W2023826034 cites W1995716366 @default.
- W2023826034 cites W1997670728 @default.
- W2023826034 cites W1998255137 @default.
- W2023826034 cites W1999591105 @default.
- W2023826034 cites W2000981078 @default.
- W2023826034 cites W2006573558 @default.
- W2023826034 cites W2010500827 @default.
- W2023826034 cites W2011907603 @default.
- W2023826034 cites W2017519742 @default.
- W2023826034 cites W2020493358 @default.
- W2023826034 cites W2025821013 @default.
- W2023826034 cites W2026124261 @default.
- W2023826034 cites W2030537346 @default.
- W2023826034 cites W2032353883 @default.
- W2023826034 cites W2034064964 @default.
- W2023826034 cites W2034073392 @default.
- W2023826034 cites W2034993026 @default.
- W2023826034 cites W2035348212 @default.
- W2023826034 cites W2036519126 @default.
- W2023826034 cites W2045468193 @default.
- W2023826034 cites W2045873723 @default.
- W2023826034 cites W2048838314 @default.
- W2023826034 cites W2049547244 @default.
- W2023826034 cites W2053889157 @default.
- W2023826034 cites W2065716393 @default.
- W2023826034 cites W2067818732 @default.
- W2023826034 cites W2071946945 @default.
- W2023826034 cites W2073599411 @default.
- W2023826034 cites W2079119292 @default.
- W2023826034 cites W2079223115 @default.
- W2023826034 cites W2082581761 @default.
- W2023826034 cites W2083372622 @default.
- W2023826034 cites W2084468919 @default.
- W2023826034 cites W2084824353 @default.
- W2023826034 cites W2088023367 @default.
- W2023826034 cites W2093467487 @default.
- W2023826034 cites W2093776977 @default.
- W2023826034 cites W2093842873 @default.
- W2023826034 cites W2095333719 @default.
- W2023826034 cites W2101024924 @default.
- W2023826034 cites W2104662981 @default.
- W2023826034 cites W2107331682 @default.
- W2023826034 cites W2113211383 @default.
- W2023826034 cites W2115472066 @default.
- W2023826034 cites W2116393970 @default.
- W2023826034 cites W2118444588 @default.
- W2023826034 cites W2121291175 @default.
- W2023826034 cites W2126389915 @default.
- W2023826034 cites W2134514535 @default.
- W2023826034 cites W2139429540 @default.
- W2023826034 cites W2141076040 @default.
- W2023826034 cites W2146479170 @default.
- W2023826034 cites W2152055261 @default.
- W2023826034 cites W2157114107 @default.
- W2023826034 cites W2161569042 @default.
- W2023826034 cites W2163354764 @default.
- W2023826034 cites W2163727727 @default.
- W2023826034 cites W2167632684 @default.
- W2023826034 cites W2168369189 @default.
- W2023826034 cites W2171974712 @default.
- W2023826034 cites W2172196352 @default.
- W2023826034 cites W2318704384 @default.
- W2023826034 cites W2327287238 @default.
- W2023826034 cites W4230112911 @default.
- W2023826034 cites W4232493467 @default.
- W2023826034 cites W4296791294 @default.
- W2023826034 doi "https://doi.org/10.1016/j.semcdb.2011.10.019" @default.
- W2023826034 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3288643" @default.
- W2023826034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22040911" @default.
- W2023826034 hasPublicationYear "2012" @default.
- W2023826034 type Work @default.
- W2023826034 sameAs 2023826034 @default.
- W2023826034 citedByCount "79" @default.
- W2023826034 countsByYear W20238260342012 @default.
- W2023826034 countsByYear W20238260342013 @default.
- W2023826034 countsByYear W20238260342014 @default.