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• W2023830064 abstract "In two separate studies, we have obtained plasma levels of GABA in 134 psychiatric patients and 22 normal controls. Patients with a unipolar affective disorder had levels significantly lower than control (n = 58) as did patients with alcoholism (n = 10). Patients with a bipolar affective disorder had levels significantly higher than control when manic (n = 28) and also when euthymic on lithium prophylaxis (n = 17), but levels in the control range when depressed (n = 4). Patients with schizophrenia demonstrated a high degree of variability in their levels of plasma GABA but were not statistically different from control (n = 36). Patients with unipolar depression who received a dexamethasone suppression test had no correlation between nonsuppression of cortisol secretion and plasma levels of GABA. Diagnostic and research implication of plasma GABA in psychiatric illness are discussed." @default.
• W2023830064 created "2016-06-24" @default.
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• W2023830064 date "1984-04-01" @default.
• W2023830064 modified "2023-09-27" @default.
• W2023830064 title "Plasma GABA levels in psychiatric illness" @default.
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• W2023830064 doi "https://doi.org/10.1016/0165-0327(84)90018-1" @default.
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