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• W2023832812 abstract "The percentage of CD5+ B lymphocytes, the prevalence of islet cell antibodies (ICA) and of anti-insulin autoantibodies (IAA) and HLA-A-B-C and DR antigens were studied in 32 newly diagnosed insulin-dependent diabetes mellitus (IDDM) patients, in 12 non-insulin-dependent diabetes mellitus (NIDDM) patients and in 12 healthy subjects. The percentage of CD5+ B lymphocytes ranged from 18% to 51.2% (mean 40.3±11%) in IDDM patients, whereas in NIDDM patients and in controls it ranged from 20% to 25.2%, (mean 21.3±4.1%) and from 16% to 24%, (mean 19.3±1.9%), respectively ( P <0.01 vs. NIDDM patients and vs. controls). There was no correlation between a higher percentage of CD5+ B lymphocytes and the presence of ICA and/or IAA, and their titres, and/or of any HLA-A-B-C and DR antigens. Thus, an enhanced percentage of CD5+ B lymphocytes may be present in newly diagnosed IDDM patients; the possible role of this cell type in the pathogenesis of IDDM needs further investigation." @default.
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• W2023832812 date "1990-01-01" @default.
• W2023832812 modified "2023-10-14" @default.
• W2023832812 title "Enhanced percentage of CD5+ B lymphocytes in newly diagnosed IDDM patients" @default.
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• W2023832812 doi "https://doi.org/10.1016/0165-2478(90)90194-u" @default.
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