FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023842409> ?p ?o ?g. }

• W2023842409 endingPage "177" @default.
• W2023842409 startingPage "169" @default.
• W2023842409 abstract "Bio-artificial livers (BAL) with microencapsulated hepatocytes have the typical limitations in maintaining hepatocyte functions, mechanical stability and uniform perfusion in packed or fluidized-bed bioreactors. We have previously developed microcapsules with enhanced hepatocyte functions. Here we have introduced a fibrin network inside microcapsules by (1) mixing collagen and fibrinogen with the encapsulated hepatocytes to support the cells; (2) submerging the microcapsules into a thrombin solution to induce the formation of an insoluble fibrin network inside the microcapsules. Fracture analysis on the microcapsules revealed significant improvement in mechanical stability. We have also introduced different amounts of gold nano-particles into microcapsules to achieve different densities for uniform bioreactor perfusion. These gold nano-particles also improved the mechanical stability of the microcapsules. Both the fibrin network and gold nano-particles exhibited the additional benefits of enhancing certain bio-functions of the encapsulated hepatocytes. The applications of these improved microcapsules in the development of bio-artificial livers are discussed." @default.
• W2023842409 created "2016-06-24" @default.
• W2023842409 creator A5014738248 @default.
• W2023842409 creator A5048501876 @default.
• W2023842409 creator A5054682300 @default.
• W2023842409 creator A5073850043 @default.
• W2023842409 date "2004-07-01" @default.
• W2023842409 modified "2023-09-26" @default.
• W2023842409 title "Improving mechanical stability and density distribution of hepatocyte microcapsules by fibrin clot and gold nano-particles" @default.
• W2023842409 cites W1490154674 @default.
• W2023842409 cites W1970178901 @default.
• W2023842409 cites W1987134604 @default.
• W2023842409 cites W2012601593 @default.
• W2023842409 cites W2014793308 @default.
• W2023842409 cites W2022282748 @default.
• W2023842409 cites W2023248908 @default.
• W2023842409 cites W2045266552 @default.
• W2023842409 cites W2048652797 @default.
• W2023842409 cites W2077246325 @default.
• W2023842409 cites W2116320890 @default.
• W2023842409 cites W2120839771 @default.
• W2023842409 cites W2142874501 @default.
• W2023842409 cites W2148549699 @default.
• W2023842409 cites W2157859754 @default.
• W2023842409 cites W2168491915 @default.
• W2023842409 cites W2173082032 @default.
• W2023842409 cites W4376454013 @default.
• W2023842409 cites W2047377178 @default.
• W2023842409 doi "https://doi.org/10.1016/j.jbiotec.2004.02.018" @default.
• W2023842409 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15219403" @default.
• W2023842409 hasPublicationYear "2004" @default.
• W2023842409 type Work @default.
• W2023842409 sameAs 2023842409 @default.
• W2023842409 citedByCount "10" @default.
• W2023842409 countsByYear W20238424092015 @default.
• W2023842409 countsByYear W20238424092016 @default.
• W2023842409 countsByYear W20238424092017 @default.
• W2023842409 countsByYear W20238424092018 @default.
• W2023842409 countsByYear W20238424092022 @default.
• W2023842409 crossrefType "journal-article" @default.
• W2023842409 hasAuthorship W2023842409A5014738248 @default.
• W2023842409 hasAuthorship W2023842409A5048501876 @default.
• W2023842409 hasAuthorship W2023842409A5054682300 @default.
• W2023842409 hasAuthorship W2023842409A5073850043 @default.
• W2023842409 hasConcept C12554922 @default.
• W2023842409 hasConcept C127413603 @default.
• W2023842409 hasConcept C136229726 @default.
• W2023842409 hasConcept C159985019 @default.
• W2023842409 hasConcept C168170006 @default.
• W2023842409 hasConcept C171250308 @default.
• W2023842409 hasConcept C178790620 @default.
• W2023842409 hasConcept C185592680 @default.
• W2023842409 hasConcept C192562407 @default.
• W2023842409 hasConcept C202751555 @default.
• W2023842409 hasConcept C203014093 @default.
• W2023842409 hasConcept C2776200302 @default.
• W2023842409 hasConcept C2777292125 @default.
• W2023842409 hasConcept C2779036427 @default.
• W2023842409 hasConcept C2780357685 @default.
• W2023842409 hasConcept C42360764 @default.
• W2023842409 hasConcept C54173615 @default.
• W2023842409 hasConcept C55493867 @default.
• W2023842409 hasConcept C71924100 @default.
• W2023842409 hasConcept C86803240 @default.
• W2023842409 hasConcept C89560881 @default.
• W2023842409 hasConceptScore W2023842409C12554922 @default.
• W2023842409 hasConceptScore W2023842409C127413603 @default.
• W2023842409 hasConceptScore W2023842409C136229726 @default.
• W2023842409 hasConceptScore W2023842409C159985019 @default.
• W2023842409 hasConceptScore W2023842409C168170006 @default.
• W2023842409 hasConceptScore W2023842409C171250308 @default.
• W2023842409 hasConceptScore W2023842409C178790620 @default.
• W2023842409 hasConceptScore W2023842409C185592680 @default.
• W2023842409 hasConceptScore W2023842409C192562407 @default.
• W2023842409 hasConceptScore W2023842409C202751555 @default.
• W2023842409 hasConceptScore W2023842409C203014093 @default.
• W2023842409 hasConceptScore W2023842409C2776200302 @default.
• W2023842409 hasConceptScore W2023842409C2777292125 @default.
• W2023842409 hasConceptScore W2023842409C2779036427 @default.
• W2023842409 hasConceptScore W2023842409C2780357685 @default.
• W2023842409 hasConceptScore W2023842409C42360764 @default.
• W2023842409 hasConceptScore W2023842409C54173615 @default.
• W2023842409 hasConceptScore W2023842409C55493867 @default.
• W2023842409 hasConceptScore W2023842409C71924100 @default.
• W2023842409 hasConceptScore W2023842409C86803240 @default.
• W2023842409 hasConceptScore W2023842409C89560881 @default.
• W2023842409 hasIssue "2" @default.
• W2023842409 hasLocation W20238424091 @default.
• W2023842409 hasLocation W20238424092 @default.
• W2023842409 hasOpenAccess W2023842409 @default.
• W2023842409 hasPrimaryLocation W20238424091 @default.
• W2023842409 hasRelatedWork W2008483939 @default.
• W2023842409 hasRelatedWork W2033799196 @default.
• W2023842409 hasRelatedWork W2057828602 @default.
• W2023842409 hasRelatedWork W2076058780 @default.
• W2023842409 hasRelatedWork W2160404471 @default.
• W2023842409 hasRelatedWork W2177069194 @default.
• W2023842409 hasRelatedWork W2413494355 @default.

• next