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- W2023863325 abstract "The inhibitory effect of various compounds on insect cuticle formation was investigated using the cultured larval integument of rice stem borer, Chilo suppressalis WALKER. The effect of 2,6-difluoro- and 2,6-dichloro-benzoyl-4-chlorophenylurea was very high, the concentrations required to suppress the new cuticular growth to 50% of the control (I50) being 0.083 and 0.58 μm, respectively. The I50 values for 2,4-dinitro- and pentachloro-phenol and other uncouples were observed over the range of 2.6–115 μm. Some N-(2′,4′-dinitrophenyl)-glucosamine derivatives, which were designed as substrate analogs of chitin biosynthesis, inhibited this new cuticle development. The most effective glucosamine derivative was methyl 2,6-di-(2′,4′-dinitroanilino)-2,6-dideoxy-α-d-glucopyranoside (I50 = 1.58 μm). Protein synthesis inhibitors such as cycloheximide and puromycin were quite potent with an I50 value of 2.0 and 6.3 μm, respectively. The present system was shown to be very sensitive as a bioassay procedure for potenti..." @default.
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- W2023863325 date "1983-07-01" @default.
- W2023863325 modified "2023-09-24" @default.
- W2023863325 title "Cultured Integument ofChilo suppressalisas a Bioassay System of Insect Growth Regulators" @default.
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- W2023863325 doi "https://doi.org/10.1080/00021369.1983.10865825" @default.
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