FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023872285> ?p ?o ?g. }

• W2023872285 endingPage "172" @default.
• W2023872285 startingPage "165" @default.
• W2023872285 abstract "A new method has been developed to measure the cross-sectional area (CSA) of scala media in the living cochlea. The method has some advantages over histological methods, in which tissues may shrink or move during processing. In the present study, scala media CSA was measured in the second turn of guinea-pig cochleas in which endolymphatic hydrops was induced surgically. The area measurement method used an iontophoretic injection of a volume marker into scala media, during which the concentration of marker in endolymph was monitored with an ion-selective microelectrode. The measured marker concentration was inversely proportional to the CSA of endolymph.The marker we used was the anion arsenic hexafluoride (AsF−6), which was almost ideal for the purpose as it was retained well in endolymph. Area was measured in normal animals and in hydropic animals at times from 4 days to 16 weeks after endolymphatic duct obstruction. The results showed that hydrops develops within days of ablation of the endolymphatic duct. The degree of hydrops was compared with electrophysiological measures of function, including the endocochlear potential, action potential thresholds and the amplitudes of the cochlear microphonic, summating potential and action potentials. In the initial stages of hydrops development, electrophysiological changes were small. In contrast, there were marked functional changes between 8 and 16 weeks, when endolymph volume was no longer increasing. These data support earlier studies which have shown that dysfunction in the hydropic cochlea does not correlate directly with the degree of endolymphatic hydrops. If the same is true for dysfunction in the ears of patients with Ménière's Disease, then it may not be possible to restore normal function simply by alleviating the hydrops. Furthermore, if dysfunction depends on factors other than the degree of hydrops, it may be possible to alleviate symptoms in ways other than by directly reducing hydrops." @default.
• W2023872285 created "2016-06-24" @default.
• W2023872285 creator A5028338620 @default.
• W2023872285 creator A5074796325 @default.
• W2023872285 date "1994-04-01" @default.
• W2023872285 modified "2023-10-16" @default.
• W2023872285 title "Time course of endolymph volume increase in experimental hydrops measured in vivo with an ionic volume marker" @default.
• W2023872285 cites W1968899322 @default.
• W2023872285 cites W1969221205 @default.
• W2023872285 cites W1984195942 @default.
• W2023872285 cites W1985558422 @default.
• W2023872285 cites W2002185450 @default.
• W2023872285 cites W2004586180 @default.
• W2023872285 cites W2017036242 @default.
• W2023872285 cites W2023152374 @default.
• W2023872285 cites W2055238504 @default.
• W2023872285 cites W2072681852 @default.
• W2023872285 cites W2076100296 @default.
• W2023872285 cites W2079079381 @default.
• W2023872285 cites W2087312423 @default.
• W2023872285 cites W2096629504 @default.
• W2023872285 cites W2102797954 @default.
• W2023872285 cites W2105545009 @default.
• W2023872285 cites W2109875138 @default.
• W2023872285 cites W2114415505 @default.
• W2023872285 cites W2209269784 @default.
• W2023872285 cites W2210712918 @default.
• W2023872285 cites W2290889097 @default.
• W2023872285 cites W2321912028 @default.
• W2023872285 cites W2433344606 @default.
• W2023872285 doi "https://doi.org/10.1016/0378-5955(94)90184-8" @default.
• W2023872285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7518819" @default.
• W2023872285 hasPublicationYear "1994" @default.
• W2023872285 type Work @default.
• W2023872285 sameAs 2023872285 @default.
• W2023872285 citedByCount "28" @default.
• W2023872285 countsByYear W20238722852013 @default.
• W2023872285 countsByYear W20238722852017 @default.
• W2023872285 countsByYear W20238722852018 @default.
• W2023872285 countsByYear W20238722852020 @default.
• W2023872285 crossrefType "journal-article" @default.
• W2023872285 hasAuthorship W2023872285A5028338620 @default.
• W2023872285 hasAuthorship W2023872285A5074796325 @default.
• W2023872285 hasConcept C105702510 @default.
• W2023872285 hasConcept C126322002 @default.
• W2023872285 hasConcept C151626666 @default.
• W2023872285 hasConcept C185263204 @default.
• W2023872285 hasConcept C185592680 @default.
• W2023872285 hasConcept C2777220873 @default.
• W2023872285 hasConcept C2778500370 @default.
• W2023872285 hasConcept C2778969067 @default.
• W2023872285 hasConcept C2779134260 @default.
• W2023872285 hasConcept C2780130748 @default.
• W2023872285 hasConcept C2780865074 @default.
• W2023872285 hasConcept C2780921233 @default.
• W2023872285 hasConcept C2781094566 @default.
• W2023872285 hasConcept C2781098194 @default.
• W2023872285 hasConcept C71924100 @default.
• W2023872285 hasConceptScore W2023872285C105702510 @default.
• W2023872285 hasConceptScore W2023872285C126322002 @default.
• W2023872285 hasConceptScore W2023872285C151626666 @default.
• W2023872285 hasConceptScore W2023872285C185263204 @default.
• W2023872285 hasConceptScore W2023872285C185592680 @default.
• W2023872285 hasConceptScore W2023872285C2777220873 @default.
• W2023872285 hasConceptScore W2023872285C2778500370 @default.
• W2023872285 hasConceptScore W2023872285C2778969067 @default.
• W2023872285 hasConceptScore W2023872285C2779134260 @default.
• W2023872285 hasConceptScore W2023872285C2780130748 @default.
• W2023872285 hasConceptScore W2023872285C2780865074 @default.
• W2023872285 hasConceptScore W2023872285C2780921233 @default.
• W2023872285 hasConceptScore W2023872285C2781094566 @default.
• W2023872285 hasConceptScore W2023872285C2781098194 @default.
• W2023872285 hasConceptScore W2023872285C71924100 @default.
• W2023872285 hasIssue "1-2" @default.
• W2023872285 hasLocation W20238722851 @default.
• W2023872285 hasLocation W20238722852 @default.
• W2023872285 hasOpenAccess W2023872285 @default.
• W2023872285 hasPrimaryLocation W20238722851 @default.
• W2023872285 hasRelatedWork W1971403829 @default.
• W2023872285 hasRelatedWork W1975238546 @default.
• W2023872285 hasRelatedWork W2023872285 @default.
• W2023872285 hasRelatedWork W2031551838 @default.
• W2023872285 hasRelatedWork W2102773342 @default.
• W2023872285 hasRelatedWork W2103575893 @default.
• W2023872285 hasRelatedWork W2161867220 @default.
• W2023872285 hasRelatedWork W2264861828 @default.
• W2023872285 hasRelatedWork W2897108740 @default.
• W2023872285 hasRelatedWork W4239812629 @default.
• W2023872285 hasVolume "74" @default.
• W2023872285 isParatext "false" @default.
• W2023872285 isRetracted "false" @default.
• W2023872285 magId "2023872285" @default.
• W2023872285 workType "article" @default.