FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023872394> ?p ?o ?g. }

• W2023872394 endingPage "C1468" @default.
• W2023872394 startingPage "C1457" @default.
• W2023872394 abstract "TRPA1 is a nonselective cation channel belonging to the transient receptor potential (TRP) family that is expressed in peripheral sensory neurons and may play important roles in pain perception and inflammation. We found that agonist stimulation of TRPA1, along with other members of the TRP family (TRPV1–4 and TRPM8), can induce the appearance of a large pore permeable to large organic cations such as Yo-Pro (YP) and N-methyl-d-glucamine, in an agonist and divalent cation-dependent manner. YP uptake was not inhibited by a panel of putative gap junction/pannexin blockers, suggesting that gap junction proteins are not required in this process. Our data suggest that changes in the TRP channel selectivity filter itself result in a progressive but reversible pore dilation process, a process that is under strong regulation by external calcium ions. Our data suggest that calcium plays a novel role in setting the amount of time TRPA1 channels spend in a dilated state providing a mechanism that may limit sensory neuron activation by painful or irritating substances." @default.
• W2023872394 created "2016-06-24" @default.
• W2023872394 creator A5015103768 @default.
• W2023872394 creator A5055176739 @default.
• W2023872394 creator A5072777316 @default.
• W2023872394 date "2010-06-01" @default.
• W2023872394 modified "2023-10-02" @default.
• W2023872394 title "Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation" @default.
• W2023872394 cites W1524500351 @default.
• W2023872394 cites W1595178772 @default.
• W2023872394 cites W1903479391 @default.
• W2023872394 cites W1965425684 @default.
• W2023872394 cites W1971566600 @default.
• W2023872394 cites W1973806783 @default.
• W2023872394 cites W1980798939 @default.
• W2023872394 cites W1981478519 @default.
• W2023872394 cites W1983671012 @default.
• W2023872394 cites W1987879958 @default.
• W2023872394 cites W1993207284 @default.
• W2023872394 cites W2000429979 @default.
• W2023872394 cites W2002201604 @default.
• W2023872394 cites W2005505879 @default.
• W2023872394 cites W2010795846 @default.
• W2023872394 cites W2011350367 @default.
• W2023872394 cites W2020833052 @default.
• W2023872394 cites W2021879636 @default.
• W2023872394 cites W2022262895 @default.
• W2023872394 cites W2025106506 @default.
• W2023872394 cites W2028688696 @default.
• W2023872394 cites W2028818251 @default.
• W2023872394 cites W2053357507 @default.
• W2023872394 cites W2059768579 @default.
• W2023872394 cites W2062978707 @default.
• W2023872394 cites W2066784771 @default.
• W2023872394 cites W2079006543 @default.
• W2023872394 cites W2079901569 @default.
• W2023872394 cites W2090859289 @default.
• W2023872394 cites W2098210944 @default.
• W2023872394 cites W2102694854 @default.
• W2023872394 cites W2106166956 @default.
• W2023872394 cites W2107057154 @default.
• W2023872394 cites W2109644936 @default.
• W2023872394 cites W2110383467 @default.
• W2023872394 cites W2110511140 @default.
• W2023872394 cites W2113278451 @default.
• W2023872394 cites W2120229762 @default.
• W2023872394 cites W2121817851 @default.
• W2023872394 cites W2129326126 @default.
• W2023872394 cites W2135562316 @default.
• W2023872394 cites W2140880966 @default.
• W2023872394 cites W2141361237 @default.
• W2023872394 cites W2141717362 @default.
• W2023872394 cites W2142715166 @default.
• W2023872394 cites W2145652492 @default.
• W2023872394 cites W2152026502 @default.
• W2023872394 cites W2156346381 @default.
• W2023872394 cites W2157577807 @default.
• W2023872394 cites W2161400125 @default.
• W2023872394 cites W2168210103 @default.
• W2023872394 doi "https://doi.org/10.1152/ajpcell.00489.2009" @default.
• W2023872394 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20457836" @default.
• W2023872394 hasPublicationYear "2010" @default.
• W2023872394 type Work @default.
• W2023872394 sameAs 2023872394 @default.
• W2023872394 citedByCount "93" @default.
• W2023872394 countsByYear W20238723942012 @default.
• W2023872394 countsByYear W20238723942013 @default.
• W2023872394 countsByYear W20238723942014 @default.
• W2023872394 countsByYear W20238723942015 @default.
• W2023872394 countsByYear W20238723942016 @default.
• W2023872394 countsByYear W20238723942017 @default.
• W2023872394 countsByYear W20238723942018 @default.
• W2023872394 countsByYear W20238723942019 @default.
• W2023872394 countsByYear W20238723942020 @default.
• W2023872394 countsByYear W20238723942021 @default.
• W2023872394 countsByYear W20238723942022 @default.
• W2023872394 countsByYear W20238723942023 @default.
• W2023872394 crossrefType "journal-article" @default.
• W2023872394 hasAuthorship W2023872394A5015103768 @default.
• W2023872394 hasAuthorship W2023872394A5055176739 @default.
• W2023872394 hasAuthorship W2023872394A5072777316 @default.
• W2023872394 hasConcept C12554922 @default.
• W2023872394 hasConcept C15490471 @default.
• W2023872394 hasConcept C155164980 @default.
• W2023872394 hasConcept C160145004 @default.
• W2023872394 hasConcept C169760540 @default.
• W2023872394 hasConcept C170493617 @default.
• W2023872394 hasConcept C172659308 @default.
• W2023872394 hasConcept C178790620 @default.
• W2023872394 hasConcept C185592680 @default.
• W2023872394 hasConcept C18699975 @default.
• W2023872394 hasConcept C201571599 @default.
• W2023872394 hasConcept C24998067 @default.
• W2023872394 hasConcept C2778938600 @default.
• W2023872394 hasConcept C30979828 @default.
• W2023872394 hasConcept C519063684 @default.
• W2023872394 hasConcept C55493867 @default.
• W2023872394 hasConcept C74884574 @default.

• next