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- W2023876475 abstract "The title compound, C(21)H(28)O, was isolated from the cytotoxic lipid extract of the Fidjian soft coral Nephthea sp. The steroid showed inhibitory activity to human colon adenocarcinoma SW480 cells (IC(50) = 2.5 µg ml(-1)). The mol-ecular structure indicates that the A ring is almost planar (r.m.s. deviation = 0.032 Å), the B and C rings adopt chair conformations and the five-membered D ring is a half-chair. The B/C and C/D ring junctions are trans-fused." @default.
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- W2023876475 date "2010-07-17" @default.
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- W2023876475 title "Pregna-1,4,20-trien-3-one, a cytotoxic marine steroid from the marine soft coral<i>Nephthea</i>sp." @default.
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- W2023876475 doi "https://doi.org/10.1107/s1600536810027352" @default.
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