FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023878873> ?p ?o ?g. }

• W2023878873 endingPage "573" @default.
• W2023878873 startingPage "567" @default.
• W2023878873 abstract "Se hizo un análisis farmacoeconómico para comparar la eficiencia de dos tratamientos en la exacerbación aguda de la bronquitis crónica: telitromicina y cefuroxima-axetil. Análisis retrospectivo, modelizado mediante un árbol de decisiones. La eficacia de los tratamientos se estimó a partir de un ensayo clínico, aleatorizado y doble ciego en el que se compararon 800 mg/día (5 días) de telitromicina con 1.000 mg/día (10 días) de cefuroxima-axetilo en pacientes con exacerbación aguda de la bronquitis crónica (140 y 142, respectivamente). La utilización de recursos se estimó a partir del ensayo clínico y de fuentes españolas y los costes unitarios mediante una base de datos de costes sanitarios. El modelo fue validado por un panel de expertos clínicos españoles. Debido a que el ensayo clínico se diseñó para demostrar equivalencia, no hubo diferencias significativas de eficacia entre los tratamientos (con una tasa de curación clínica del 86,4% y el 83,1%, respectivamente), por lo que se hizo un análisis de minimización de costes. En el caso básico, el coste medio de la enfermedad por paciente fue de 174,83 euros con telitromicina y de 194,68 euros con cefuroxima-axetilo (diferencia de 19,85 euros). Los resultados fueron estables en el análisis de sensibilidad, con diferencias favorables a telitromicina que oscilaron entre 18,04 y 22,25 euros. Con telitromicina se podrían ahorrar hasta 22 euros por paciente con exacerbación aguda de la bronquitis crónica. A pharmacoeconomic analysis was done to compare the efficiency of two treatments in the acute exacerbation of chronic bronchitis: telithromycin and cefuroxime-axetil. Restrospective analysis, modeled through a decision tree. The effectiveness of the treatments was estimated through a randomized and doubleblind clinical trial in which 800 mg/day (5 days) of telithromycin were compared with 1,000 mg/day (10 days) of cefuroxime-axetil in patients with acute exacerbation of chronic bronchitis (140 and 142 patients, respectively). Resources use was estimated from clinical trial and from Spanish data, and the unit costs through a health costs dabatase. The model was validated by a panel of Spanish clinical experts. Since the clinical trial was designed to demonstrate equivalence, there were no significant differences of effectiveness among both treatments (with a rate of clinical cure of 86.4% and 83.1%, respectively) which means that an analysis of costs minimization was done. In the average case, the average cost of the disease by patient was 174.83 € with telithromycin and 194.68 € with cefuroximeaxetil (a difference of 19.85 €). The results were maintained in the analysis of sensitivity, with favorable differences for telithromycin that ranged between 18.04 € and 22.25 €. With telithromycin up to 22 € by patient with acute exacerbation of chronic bronchitis could be saved, in comparison with cefuroxime-axetil." @default.
• W2023878873 created "2016-06-24" @default.
• W2023878873 creator A5001266677 @default.
• W2023878873 creator A5006573100 @default.
• W2023878873 creator A5023143264 @default.
• W2023878873 creator A5046339713 @default.
• W2023878873 creator A5048226395 @default.
• W2023878873 creator A5062986605 @default.
• W2023878873 creator A5085090058 @default.
• W2023878873 date "2004-01-01" @default.
• W2023878873 modified "2023-10-03" @default.
• W2023878873 title "Análisis farmacoeconómico del tratamiento de pacientes con exacerbación aguda de la bronquitis crónica con telitromicina o cefuroxima-axetilo" @default.
• W2023878873 cites W1968121624 @default.
• W2023878873 cites W1983275348 @default.
• W2023878873 cites W2036157872 @default.
• W2023878873 cites W2103849265 @default.
• W2023878873 cites W2117377748 @default.
• W2023878873 cites W2117899621 @default.
• W2023878873 cites W2131871606 @default.
• W2023878873 cites W2150712216 @default.
• W2023878873 cites W2151804128 @default.
• W2023878873 cites W2163366346 @default.
• W2023878873 cites W5246732 @default.
• W2023878873 cites W83087865 @default.
• W2023878873 doi "https://doi.org/10.1016/s0014-2565(04)71549-0" @default.
• W2023878873 hasPublicationYear "2004" @default.
• W2023878873 type Work @default.
• W2023878873 sameAs 2023878873 @default.
• W2023878873 citedByCount "2" @default.
• W2023878873 crossrefType "journal-article" @default.
• W2023878873 hasAuthorship W2023878873A5001266677 @default.
• W2023878873 hasAuthorship W2023878873A5006573100 @default.
• W2023878873 hasAuthorship W2023878873A5023143264 @default.
• W2023878873 hasAuthorship W2023878873A5046339713 @default.
• W2023878873 hasAuthorship W2023878873A5048226395 @default.
• W2023878873 hasAuthorship W2023878873A5062986605 @default.
• W2023878873 hasAuthorship W2023878873A5085090058 @default.
• W2023878873 hasConcept C138885662 @default.
• W2023878873 hasConcept C15708023 @default.
• W2023878873 hasConcept C29456083 @default.
• W2023878873 hasConcept C71924100 @default.
• W2023878873 hasConceptScore W2023878873C138885662 @default.
• W2023878873 hasConceptScore W2023878873C15708023 @default.
• W2023878873 hasConceptScore W2023878873C29456083 @default.
• W2023878873 hasConceptScore W2023878873C71924100 @default.
• W2023878873 hasIssue "11" @default.
• W2023878873 hasLocation W20238788731 @default.
• W2023878873 hasOpenAccess W2023878873 @default.
• W2023878873 hasPrimaryLocation W20238788731 @default.
• W2023878873 hasRelatedWork W1489783725 @default.
• W2023878873 hasRelatedWork W1506200166 @default.
• W2023878873 hasRelatedWork W2039318446 @default.
• W2023878873 hasRelatedWork W2080531066 @default.
• W2023878873 hasRelatedWork W2373994074 @default.
• W2023878873 hasRelatedWork W2748952813 @default.
• W2023878873 hasRelatedWork W2780146991 @default.
• W2023878873 hasRelatedWork W2896609434 @default.
• W2023878873 hasRelatedWork W2899084033 @default.
• W2023878873 hasRelatedWork W3012411836 @default.
• W2023878873 hasVolume "204" @default.
• W2023878873 isParatext "false" @default.
• W2023878873 isRetracted "false" @default.
• W2023878873 magId "2023878873" @default.
• W2023878873 workType "article" @default.