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- W2023879935 abstract "We analyzed myelin basic protein (MBP) specific T cell hybridoma clones from (B10.PL x PL/J)F1 mice. MBP-reacting T cell hybridomas from F1 mice preferentially expressed B10.PL TcraV2.3 (53%) and B10.PL TcraV4.2 (13%) with minor expression of TcraV4.4 (13%) gene segments. A dominant expression of TcrbV8.2 (73%) accompanying with TcrbV8.1 (20%) and TcrbV13 (7%) gene segments have been identified in these MBP-reacting T cell hybridomas from F1 mice. There was less restrictive but non-random usage of the TcraJ and TcrbJ gene segments. Overall, the MBP-reacting T cell hybridomas from (B10.PL x PL/J)F1 mice were dominated by the MBP-reacting T cell pattern seen in B10.PL mice." @default.
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- W2023879935 date "1997-12-01" @default.
- W2023879935 modified "2023-09-23" @default.
- W2023879935 title "TCRV and TCRJ gene usage in MBP responding T cells from (B10.PL×PL/J)F1 mice is biased towards that of B10.PL mice" @default.
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- W2023879935 doi "https://doi.org/10.1016/s0165-5728(97)00129-x" @default.
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