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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023883416> ?p ?o ?g. }

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• W2023883416 abstract "The discovery and SAR study of a series of 4,6-diamino-1,3,5-triazin-2-ol compounds as novel HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are reported. The lead compounds in this series showed excellent activity against wild-type and drug-resistant RT enzymes and viral strains. In addition, compounds from this series demonstrated favorable pharmacokinetic profile in rat. A preliminary modeling study was conducted to understand the binding mode of this series of compounds." @default.
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• W2023883416 date "2010-11-01" @default.
• W2023883416 modified "2023-09-23" @default.
• W2023883416 title "Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1" @default.
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• W2023883416 doi "https://doi.org/10.1016/j.bmcl.2010.09.034" @default.
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