Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023892088> ?p ?o ?g. }
- W2023892088 endingPage "21" @default.
- W2023892088 startingPage "11" @default.
- W2023892088 abstract "Abstract: The data reported here were obtained from the case-control arm of a large, comprehensive, population-based investigation of colorectal cancer incidence, etiology, and survival, the Melbourne Colorectal Cancer Study, conducted in Melbourne, Australia. This part of the case-control study was designed to identify dietary factors associated with colorectal cancer risk in 715 incident cases compared with 727 age/sex frequency-matched randomly chosen community controls, in which a quantitative assessment of all foods eaten was made. New data are presented on the potential of two groups of micronutrients as protective agents, namely, those involved in DNA methylation, synthesis, and repair (folate, methionine, and vitamins B6 and B12) and those with antioxidant properties (selenium, vitamins E and C, and lycopene). The adjusted odds ratios showed that for folate there was significant protection for rectal cancer in second and third quintiles of consumption but not for colon cancer, and this was similar for methionine consumption. Vitamin B6 consumption was significantly protective for both colon and rectal cancer at the higher quintiles, and this was similar for vitamin B12. Dietary selenium was significantly protective at middle quintiles of consumption at both cancer sites. Dietary vitamins E and C were statistically significantly protective for both colon and rectal cancer at all levels of consumption, and for both vitamins there was a dose-response effect of increasing protection, particularly so for colon cancer. Lycopene was not associated with colorectal cancer risk. A combined model included vitamins E, C, and B12 and selenium as micronutrients protective for colorectal cancer and folate, which, however, showed an increased risk at the highest level of consumption. These data support the proposition that a diet containing the dietary micronutrients involved in DNA methylation (folate, methionine, and vitamins B6 and B12) and some of those with antioxidant properties (selenium and vitamins E and C) may have a role to play in lowering colorectal cancer risk and also that such protection can be achieved by dietary means alone." @default.
- W2023892088 created "2016-06-24" @default.
- W2023892088 creator A5019208854 @default.
- W2023892088 creator A5031136758 @default.
- W2023892088 date "2006-09-01" @default.
- W2023892088 modified "2023-10-18" @default.
- W2023892088 title "Colorectal Cancer Protective Effects and the Dietary Micronutrients Folate, Methionine, Vitamins B6, B12, C, E, Selenium, and Lycopene" @default.
- W2023892088 cites W1875679514 @default.
- W2023892088 cites W1908008529 @default.
- W2023892088 cites W1933482556 @default.
- W2023892088 cites W1967322292 @default.
- W2023892088 cites W1972248527 @default.
- W2023892088 cites W1972644344 @default.
- W2023892088 cites W1972686880 @default.
- W2023892088 cites W1973225748 @default.
- W2023892088 cites W1976215418 @default.
- W2023892088 cites W1979191694 @default.
- W2023892088 cites W1995962756 @default.
- W2023892088 cites W2006113448 @default.
- W2023892088 cites W2006478345 @default.
- W2023892088 cites W2015668657 @default.
- W2023892088 cites W2019369653 @default.
- W2023892088 cites W2029935366 @default.
- W2023892088 cites W2030374973 @default.
- W2023892088 cites W2063515318 @default.
- W2023892088 cites W2065776584 @default.
- W2023892088 cites W2068510718 @default.
- W2023892088 cites W2068823733 @default.
- W2023892088 cites W2072724993 @default.
- W2023892088 cites W2073493961 @default.
- W2023892088 cites W2079118665 @default.
- W2023892088 cites W2088687515 @default.
- W2023892088 cites W2097612130 @default.
- W2023892088 cites W2104760925 @default.
- W2023892088 cites W2106727633 @default.
- W2023892088 cites W2108179587 @default.
- W2023892088 cites W2111183491 @default.
- W2023892088 cites W2116186771 @default.
- W2023892088 cites W2118400439 @default.
- W2023892088 cites W2122034322 @default.
- W2023892088 cites W2128822546 @default.
- W2023892088 cites W2136725886 @default.
- W2023892088 cites W2138178697 @default.
- W2023892088 cites W2142877787 @default.
- W2023892088 cites W2147085467 @default.
- W2023892088 cites W2165057232 @default.
- W2023892088 cites W2165423436 @default.
- W2023892088 cites W2244344295 @default.
- W2023892088 cites W2494554126 @default.
- W2023892088 cites W2790325250 @default.
- W2023892088 cites W4255483444 @default.
- W2023892088 doi "https://doi.org/10.1207/s15327914nc5601_3" @default.
- W2023892088 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17176213" @default.
- W2023892088 hasPublicationYear "2006" @default.
- W2023892088 type Work @default.
- W2023892088 sameAs 2023892088 @default.
- W2023892088 citedByCount "134" @default.
- W2023892088 countsByYear W20238920882012 @default.
- W2023892088 countsByYear W20238920882013 @default.
- W2023892088 countsByYear W20238920882014 @default.
- W2023892088 countsByYear W20238920882015 @default.
- W2023892088 countsByYear W20238920882016 @default.
- W2023892088 countsByYear W20238920882017 @default.
- W2023892088 countsByYear W20238920882018 @default.
- W2023892088 countsByYear W20238920882019 @default.
- W2023892088 countsByYear W20238920882020 @default.
- W2023892088 countsByYear W20238920882021 @default.
- W2023892088 countsByYear W20238920882022 @default.
- W2023892088 countsByYear W20238920882023 @default.
- W2023892088 crossrefType "journal-article" @default.
- W2023892088 hasAuthorship W2023892088A5019208854 @default.
- W2023892088 hasAuthorship W2023892088A5031136758 @default.
- W2023892088 hasConcept C121608353 @default.
- W2023892088 hasConcept C126322002 @default.
- W2023892088 hasConcept C142724271 @default.
- W2023892088 hasConcept C14522933 @default.
- W2023892088 hasConcept C2779750884 @default.
- W2023892088 hasConcept C2780022147 @default.
- W2023892088 hasConcept C2780234812 @default.
- W2023892088 hasConcept C28781525 @default.
- W2023892088 hasConcept C2908647359 @default.
- W2023892088 hasConcept C3020471959 @default.
- W2023892088 hasConcept C31903555 @default.
- W2023892088 hasConcept C42407357 @default.
- W2023892088 hasConcept C526805850 @default.
- W2023892088 hasConcept C71924100 @default.
- W2023892088 hasConcept C86803240 @default.
- W2023892088 hasConcept C90924648 @default.
- W2023892088 hasConcept C99454951 @default.
- W2023892088 hasConceptScore W2023892088C121608353 @default.
- W2023892088 hasConceptScore W2023892088C126322002 @default.
- W2023892088 hasConceptScore W2023892088C142724271 @default.
- W2023892088 hasConceptScore W2023892088C14522933 @default.
- W2023892088 hasConceptScore W2023892088C2779750884 @default.
- W2023892088 hasConceptScore W2023892088C2780022147 @default.
- W2023892088 hasConceptScore W2023892088C2780234812 @default.
- W2023892088 hasConceptScore W2023892088C28781525 @default.
- W2023892088 hasConceptScore W2023892088C2908647359 @default.