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- W2023892978 abstract "The interaction between EF‐Tu GTP and aminoacyl‐tRNA is shown to be influenced by mutations at site 375 of this three‐domain protein. Site 375 is located in domain II near the interface with domain I [(1984) EMBO J. 3, 113‐120]. Replacement of the alanine at this site by a threonine or valine residue results in lower binding constants with Phe‐tRNA and Tyr‐tRNA, as was evaluated by the hydrolysis protection technique. The data are discussed in the light of what is known about the three‐dimensional structure of the protein and its interaction sites with aminoacyl‐tRNA." @default.
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- W2023892978 date "1985-06-03" @default.
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- W2023892978 title "Mutant species of EF-Tu, altered at position 375, exhibit a reduced affinity for aminoacylated transfer-RNAs" @default.
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- W2023892978 doi "https://doi.org/10.1016/0014-5793(85)80739-0" @default.
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