FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023924759> ?p ?o ?g. }

• W2023924759 endingPage "94" @default.
• W2023924759 startingPage "86" @default.
• W2023924759 abstract "Supplementation with folic acid during pregnancy is known to reduce the risk of neural tube defects and low birth weight. It is thought that folate and other one-carbon intermediates might secure these clinical effects via DNA methylation. We examined the effects of folate on the human methylome using quantitative interrogation of 27,578 CpG loci associated with 14,496 genes at single-nucleotide resolution across 12 fetal cord blood samples. Consistent with previous studies, the majority of CpG dinucleotides located within CpG islands exhibited hypo-methylation while those outside CpG islands showed mid-high methylation. However, for the first time in human samples, unbiased analysis of methylation across samples revealed a significant correlation of methylation patterns with plasma homocysteine, LINE-1 methylation and birth weight centile. Additionally, CpG methylation significantly correlated with either birth weight or LINE-1 methylation were predominantly located in CpG islands. These data indicate that levels of folate-associated intermediates in cord blood reflect their influence and consequences for the fetal epigenome and potentially on pregnancy outcome. In these cases, their influence might be exerted during late gestation or reflect those present during the peri-conceptual period." @default.
• W2023924759 created "2016-06-24" @default.
• W2023924759 creator A5022180165 @default.
• W2023924759 creator A5031394822 @default.
• W2023924759 creator A5047795251 @default.
• W2023924759 creator A5055727064 @default.
• W2023924759 creator A5059715703 @default.
• W2023924759 creator A5081245556 @default.
• W2023924759 creator A5081480113 @default.
• W2023924759 date "2011-01-01" @default.
• W2023924759 modified "2023-09-29" @default.
• W2023924759 title "Quantitative, high-resolution epigenetic profiling of CpG loci identifies associations with cord blood plasma homocysteine and birth weight in humans" @default.
• W2023924759 cites W1908008529 @default.
• W2023924759 cites W1977087590 @default.
• W2023924759 cites W1977150757 @default.
• W2023924759 cites W1998970086 @default.
• W2023924759 cites W2007470097 @default.
• W2023924759 cites W2011474247 @default.
• W2023924759 cites W2021709109 @default.
• W2023924759 cites W2030251295 @default.
• W2023924759 cites W2085745662 @default.
• W2023924759 cites W2088433039 @default.
• W2023924759 cites W2089003540 @default.
• W2023924759 cites W2095329894 @default.
• W2023924759 cites W2099930946 @default.
• W2023924759 cites W2100489386 @default.
• W2023924759 cites W2103368550 @default.
• W2023924759 cites W2103673123 @default.
• W2023924759 cites W2106401558 @default.
• W2023924759 cites W2106922810 @default.
• W2023924759 cites W2114970231 @default.
• W2023924759 cites W2115443997 @default.
• W2023924759 cites W2117312367 @default.
• W2023924759 cites W2122683221 @default.
• W2023924759 cites W2123174009 @default.
• W2023924759 cites W2132693307 @default.
• W2023924759 cites W2143858605 @default.
• W2023924759 cites W2148337554 @default.
• W2023924759 cites W2148521032 @default.
• W2023924759 cites W2150490006 @default.
• W2023924759 cites W2152137902 @default.
• W2023924759 cites W2159409293 @default.
• W2023924759 cites W2163125553 @default.
• W2023924759 cites W2167015768 @default.
• W2023924759 cites W2170760271 @default.
• W2023924759 cites W2171139450 @default.
• W2023924759 cites W4301238125 @default.
• W2023924759 doi "https://doi.org/10.4161/epi.6.1.13392" @default.
• W2023924759 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3052917" @default.
• W2023924759 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20864804" @default.
• W2023924759 hasPublicationYear "2011" @default.
• W2023924759 type Work @default.
• W2023924759 sameAs 2023924759 @default.
• W2023924759 citedByCount "127" @default.
• W2023924759 countsByYear W20239247592012 @default.
• W2023924759 countsByYear W20239247592013 @default.
• W2023924759 countsByYear W20239247592014 @default.
• W2023924759 countsByYear W20239247592015 @default.
• W2023924759 countsByYear W20239247592016 @default.
• W2023924759 countsByYear W20239247592017 @default.
• W2023924759 countsByYear W20239247592018 @default.
• W2023924759 countsByYear W20239247592019 @default.
• W2023924759 countsByYear W20239247592020 @default.
• W2023924759 countsByYear W20239247592021 @default.
• W2023924759 countsByYear W20239247592022 @default.
• W2023924759 countsByYear W20239247592023 @default.
• W2023924759 crossrefType "journal-article" @default.
• W2023924759 hasAuthorship W2023924759A5022180165 @default.
• W2023924759 hasAuthorship W2023924759A5031394822 @default.
• W2023924759 hasAuthorship W2023924759A5047795251 @default.
• W2023924759 hasAuthorship W2023924759A5055727064 @default.
• W2023924759 hasAuthorship W2023924759A5059715703 @default.
• W2023924759 hasAuthorship W2023924759A5081245556 @default.
• W2023924759 hasAuthorship W2023924759A5081480113 @default.
• W2023924759 hasBestOaLocation W20239247591 @default.
• W2023924759 hasConcept C104317684 @default.
• W2023924759 hasConcept C117717151 @default.
• W2023924759 hasConcept C134018914 @default.
• W2023924759 hasConcept C140173407 @default.
• W2023924759 hasConcept C150194340 @default.
• W2023924759 hasConcept C154253233 @default.
• W2023924759 hasConcept C16685009 @default.
• W2023924759 hasConcept C172680121 @default.
• W2023924759 hasConcept C190727270 @default.
• W2023924759 hasConcept C2777090595 @default.
• W2023924759 hasConcept C2779234561 @default.
• W2023924759 hasConcept C2780914630 @default.
• W2023924759 hasConcept C33288867 @default.
• W2023924759 hasConcept C41091548 @default.
• W2023924759 hasConcept C54355233 @default.
• W2023924759 hasConcept C66322754 @default.
• W2023924759 hasConcept C71924100 @default.
• W2023924759 hasConcept C86803240 @default.
• W2023924759 hasConceptScore W2023924759C104317684 @default.
• W2023924759 hasConceptScore W2023924759C117717151 @default.
• W2023924759 hasConceptScore W2023924759C134018914 @default.
• W2023924759 hasConceptScore W2023924759C140173407 @default.
• W2023924759 hasConceptScore W2023924759C150194340 @default.

• next