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- W2023931411 abstract "Abstract The effect of monovalent cations on derepression of phosphate transport was studied. It was found that ammonium, K + and Rb + accelerate the derepression of phosphate transport produced by glucose in yeast ( Saccharomyces cerevisiae ). Na + and Li + were ineffective in accelerating derepression; Cs + produced only a minor stimulation. The concentration range of both K + and NH 4 + that accelerated derepression was similar to that required for transport to occur. In the case of ammonium, the effects seem to depend exclusively on the so-called low-affinity transport system. The effect was strongly dependent on pH, with an optimum around 6; however, the increase in the pH of the medium did not produce in itself a high increase of the depression. Derepression was dependent on the presence of glucose, and it was very low with ethanol as substrate. The mechanism seems to depend on the ability that both K + and NH 4 + have to decrease the membrane potential of the cell while transported, and not on the capacity to produce the alkalinization of the cell interior. In addition, the phenomenon depends on the presence of glucose as substrate, which indicates the involvement of some product of glucose metabolism in the mechanism, and possibly some relation to catabolic repression." @default.
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- W2023931411 date "1986-02-01" @default.
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- W2023931411 title "Effects of monovalent cations on derepression of phosphate transport in yeast" @default.
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- W2023931411 doi "https://doi.org/10.1016/0005-2736(86)90202-6" @default.
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