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• W2023940028 abstract "<h3>Objective</h3> We have previously reported that the histologic mode of invasion of oral squamous cell carcinoma (OSCC) is a significant risk factor for pain. Here we sought to determine whether pain is a risk factor for poor prognosis in patients with OSCC. <h3>Study design</h3> We evaluated the relationships between overall survival rates and clinicopathologic variables, including gender, age, T- and N-stages, pathologic findings, and pain in 109 consecutive patients with untreated OSCC. <h3>Results</h3> Of these 109 patients, 40 (37%) reported spontaneous pain. Univariate analysis showed that the overall survival rates of patients with spontaneous pain was significantly lower than those of patients without pain (<i>P</i> = .002). Multivariate analysis revealed that spontaneous pain and N-stage were significant independent predictors of overall survival rates. <h3>Conclusions</h3> This is the first report showing that spontaneous pain before treatment may be associated with poor prognosis in patients with OSCC." @default.
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• W2023940028 date "2011-05-01" @default.
• W2023940028 modified "2023-10-01" @default.
• W2023940028 title "Pain may predict poor prognosis in patients with oral squamous cell carcinoma" @default.
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• W2023940028 doi "https://doi.org/10.1016/j.tripleo.2010.11.033" @default.
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