FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023942693> ?p ?o ?g. }

• W2023942693 endingPage "514" @default.
• W2023942693 startingPage "507" @default.
• W2023942693 abstract "To improve survival of children with acute lymphoblastic leukemia (ALL) in the authors' institute and to define significant prognostic factors.This study included 154 children with newly diagnosed ALL below the age of 18 years during the period August 1, 1998, to December 31, 2000. All patients were treated according to the NCI, Cairo, Egypt, treatment protocol modified from study XIII for high-risk ALL of St. Jude Children's Research Hospital.B-cell precursor phenotype was encountered in 73.4% of patients, T-cell in 26.6%. According to NCI/Rome criteria for risk classification, 58.4% of patients were in the high-risk group (90% of T-lineage compared with 47% of B-lineage ALL, P < 0.001). Nine patients (5.8%) died during induction and 10 patients (6.5%) failed to achieve remission. With a median follow-up of 43 months, the 3-year disease-free survival and its probability at 5 years were 80 +/- 3.6% and 75.3 +/- 4%, respectively; the 3-year event-free survival and its probability at 5 years were 69 +/- 3.8% and 65.2 +/- 4%, respectively. B-cell precursor ALL had 5-year probabilities of disease-free survival and event-free survival of 80.5 +/- 4% and 71.8 +/- 4.5% compared with 60.2 +/- 8.6% and 46.7 +/- 8% for T-cell, respectively (P < 0.01, log-rank test). Prognostic factors that had a statistically significant unfavorable impact on survival by univariate analysis were age 10 years or more, central nervous system involvement, T-lineage phenotype, high-risk group, DNA index less than 1.16, and slow early response to treatment. By multivariate analysis, central nervous system involvement, high-risk group, and slow early response to treatment still had prognostic significance. Risk classification demonstrated prognostic significance for B-lineage but not T-lineage ALL.This treatment protocol was effective in improving ALL survival among patients at the authors' institute compared with previous trials, although the outcome remains lower than that in more industrialized countries. Prognostic factors defined in this study were similar to those identified by other cooperative groups." @default.
• W2023942693 created "2016-06-24" @default.
• W2023942693 creator A5009399858 @default.
• W2023942693 creator A5025842109 @default.
• W2023942693 creator A5026235635 @default.
• W2023942693 creator A5038795798 @default.
• W2023942693 creator A5047327295 @default.
• W2023942693 creator A5061391071 @default.
• W2023942693 creator A5084778434 @default.
• W2023942693 creator A5089622651 @default.
• W2023942693 date "2004-08-01" @default.
• W2023942693 modified "2023-09-27" @default.
• W2023942693 title "Outcome and Prognostic Factors of Acute Lymphoblastic Leukemia in Children at the National Cancer Institute, Egypt" @default.
• W2023942693 cites W1904793007 @default.
• W2023942693 cites W1976897003 @default.
• W2023942693 cites W2007208181 @default.
• W2023942693 cites W2007904492 @default.
• W2023942693 cites W2008532498 @default.
• W2023942693 cites W2039677781 @default.
• W2023942693 cites W2045633229 @default.
• W2023942693 cites W2062116534 @default.
• W2023942693 cites W2076426515 @default.
• W2023942693 cites W2079847585 @default.
• W2023942693 cites W2119685895 @default.
• W2023942693 cites W2154443565 @default.
• W2023942693 cites W4242108431 @default.
• W2023942693 cites W4255119797 @default.
• W2023942693 cites W59733412 @default.
• W2023942693 doi "https://doi.org/10.1097/01.mph.0000132735.93396.92" @default.
• W2023942693 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15284589" @default.
• W2023942693 hasPublicationYear "2004" @default.
• W2023942693 type Work @default.
• W2023942693 sameAs 2023942693 @default.
• W2023942693 citedByCount "27" @default.
• W2023942693 countsByYear W20239426932012 @default.
• W2023942693 countsByYear W20239426932013 @default.
• W2023942693 countsByYear W20239426932014 @default.
• W2023942693 countsByYear W20239426932017 @default.
• W2023942693 countsByYear W20239426932018 @default.
• W2023942693 countsByYear W20239426932019 @default.
• W2023942693 countsByYear W20239426932020 @default.
• W2023942693 countsByYear W20239426932022 @default.
• W2023942693 crossrefType "journal-article" @default.
• W2023942693 hasAuthorship W2023942693A5009399858 @default.
• W2023942693 hasAuthorship W2023942693A5025842109 @default.
• W2023942693 hasAuthorship W2023942693A5026235635 @default.
• W2023942693 hasAuthorship W2023942693A5038795798 @default.
• W2023942693 hasAuthorship W2023942693A5047327295 @default.
• W2023942693 hasAuthorship W2023942693A5061391071 @default.
• W2023942693 hasAuthorship W2023942693A5084778434 @default.
• W2023942693 hasAuthorship W2023942693A5089622651 @default.
• W2023942693 hasConcept C10515644 @default.
• W2023942693 hasConcept C121608353 @default.
• W2023942693 hasConcept C126322002 @default.
• W2023942693 hasConcept C144301174 @default.
• W2023942693 hasConcept C187212893 @default.
• W2023942693 hasConcept C2778461978 @default.
• W2023942693 hasConcept C2779134260 @default.
• W2023942693 hasConcept C2781107101 @default.
• W2023942693 hasConcept C2909962599 @default.
• W2023942693 hasConcept C38180746 @default.
• W2023942693 hasConcept C66339696 @default.
• W2023942693 hasConcept C71924100 @default.
• W2023942693 hasConceptScore W2023942693C10515644 @default.
• W2023942693 hasConceptScore W2023942693C121608353 @default.
• W2023942693 hasConceptScore W2023942693C126322002 @default.
• W2023942693 hasConceptScore W2023942693C144301174 @default.
• W2023942693 hasConceptScore W2023942693C187212893 @default.
• W2023942693 hasConceptScore W2023942693C2778461978 @default.
• W2023942693 hasConceptScore W2023942693C2779134260 @default.
• W2023942693 hasConceptScore W2023942693C2781107101 @default.
• W2023942693 hasConceptScore W2023942693C2909962599 @default.
• W2023942693 hasConceptScore W2023942693C38180746 @default.
• W2023942693 hasConceptScore W2023942693C66339696 @default.
• W2023942693 hasConceptScore W2023942693C71924100 @default.
• W2023942693 hasIssue "8" @default.
• W2023942693 hasLocation W20239426931 @default.
• W2023942693 hasLocation W20239426932 @default.
• W2023942693 hasOpenAccess W2023942693 @default.
• W2023942693 hasPrimaryLocation W20239426931 @default.
• W2023942693 hasRelatedWork W1987677298 @default.
• W2023942693 hasRelatedWork W2096525432 @default.
• W2023942693 hasRelatedWork W2138506229 @default.
• W2023942693 hasRelatedWork W2375628929 @default.
• W2023942693 hasRelatedWork W2386134303 @default.
• W2023942693 hasRelatedWork W2405817813 @default.
• W2023942693 hasRelatedWork W2464502384 @default.
• W2023942693 hasRelatedWork W2546819628 @default.
• W2023942693 hasRelatedWork W2616212697 @default.
• W2023942693 hasRelatedWork W635611323 @default.
• W2023942693 hasVolume "26" @default.
• W2023942693 isParatext "false" @default.
• W2023942693 isRetracted "false" @default.
• W2023942693 magId "2023942693" @default.
• W2023942693 workType "article" @default.