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- W2023952924 abstract "Mast cell degranulation and liberation of vasoactive substances during anaphylactic reaction were parallel in guinea pigs,<sup>1</sup>rats,<sup>2</sup>and mice.<sup>3</sup> It was also shown that connective tissue and choroid mast cells are both degranulated by compound 48/80.<sup>4-7</sup> In the present study the alterations of vessels and mast cells of the posterior uvea in local anaphylactic reactions are reported. <h3>Materials and Methods</h3><h3>Antigens.</h3> —(<i>a</i>) Human gamma globulin (Lederle, C-583); (<i>b</i>) Human albumin (Behringwerke, Op. Nr. 1916-D, 358/E 297). <h3>Antiserum.</h3> —Rabbit antihuman globulin containing 884μg antibody nitrogen per milliliter (Ab N). <h3>Dye.</h3> —Colloidal carbon (Gunther Wagner—C 11/ 1431a), suspended according to Biozzi et al<sup>8</sup>and injected intravenously (8 mg/100 gm body weight). <h3>Diluent.</h3> —All reagents except the carbon were dissolved in 0.15 M NaCl. <h3>Animals.</h3> —Male albino guinea pigs weighing 250 to 300 gm (uveal pigment in pigmented animals makes it difficult to detect mast cells). <h3>Experiment</h3>" @default.
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- W2023952924 date "1965-09-01" @default.
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- W2023952924 title "Mast Cells and Vessels of the Choroid of Albino Guinea Pigs During the Uveal Anaphylactic Reaction" @default.
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- W2023952924 doi "https://doi.org/10.1001/archopht.1965.00970040369016" @default.
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