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- W2023954758 abstract "Abstract The distal P III component of the frog electroretinogram has been previously shown to represent a massed receptor potential of the retina. This study, utilizing isolated frog retinas, has shown that the amplitude of the distal P III potential has a near linear relationship with the concentration of calcium. The amplitude is maximal for low concentrations of calcium and is significantly reduced with increasing concentrations of calcium. Although the amplitude of the distal P III potential was greatly influenced by the calcium concentration, there was very little effect noted on the temporal recovery of response following brief intensive stimulation as a function of the calcium concentration. The enhancement of the distal P III potential found in low calcium media is also reflected in an increase in the amplitude of the b-wave, which is generated by more proximal cells of the retina. However, a slight change of “gain” was noted in the relationship between the distal P III potential and the b-wave in the low calcium concentration media. The mode of action of calcium is discussed in terms of the regulation of ionic permeabilities and active transport mechanisms." @default.
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- W2023954758 date "1971-07-01" @default.
- W2023954758 modified "2023-09-27" @default.
- W2023954758 title "The effect of calcium on the distal P III component of the frog ERG" @default.
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- W2023954758 doi "https://doi.org/10.1016/0014-4835(71)90130-8" @default.
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