FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023956002> ?p ?o ?g. }

• W2023956002 endingPage "621" @default.
• W2023956002 startingPage "621" @default.
• W2023956002 abstract "Androgen deprivation therapy (ADT) increases the risk for fractures in patients with prostate cancer.To assess the cost-effectiveness of measuring bone mineral density (BMD) before initiating ADT followed by alendronate therapy in men with localized prostate cancer.Markov state-transition model simulating the progression of prostate cancer and the incidence of hip fracture.Published literature.A hypothetical cohort of men aged 70 years with locally advanced or high-risk localized prostate cancer starting a 2-year course of ADT after radiation therapy.Lifetime.Societal.No BMD test or alendronate therapy, a BMD test followed by selective alendronate therapy for patients with osteoporosis, or universal alendronate therapy without a BMD test.Incremental cost-effectiveness ratio (ICER), measured by cost per quality-adjusted life-year (QALY) gained.The ICERs for the strategy of a BMD test and selective alendronate therapy for patients with osteoporosis and universal alendronate therapy without a BMD test were $66,800 per QALY gained and $178,700 per QALY gained, respectively.The ICER for universal alendronate therapy without a BMD test decreased to $100,000 per QALY gained, assuming older age, a history of fractures, lower mean BMD before ADT, or a lower cost of alendronate.No evidence shows that alendronate reduces actual fracture rates in patients with prostate cancer who receive ADT. The model predicted fracture rates by using data on the surrogate BMD end point.In patients starting adjuvant ADT for locally advanced or high-risk localized prostate cancer, a BMD test followed by selective alendronate for those with osteoporosis is a cost-effective use of resources. Routine use of alendronate without a BMD test is justifiable in patients at higher risk for hip fractures." @default.
• W2023956002 created "2016-06-24" @default.
• W2023956002 creator A5001498977 @default.
• W2023956002 creator A5017288060 @default.
• W2023956002 creator A5063707394 @default.
• W2023956002 creator A5080965213 @default.
• W2023956002 date "2010-05-18" @default.
• W2023956002 modified "2023-09-26" @default.
• W2023956002 title "Cost-Effectiveness of Fracture Prevention in Men Who Receive Androgen Deprivation Therapy for Localized Prostate Cancer" @default.
• W2023956002 cites W1512398135 @default.
• W2023956002 cites W1964692065 @default.
• W2023956002 cites W1968511145 @default.
• W2023956002 cites W1970400080 @default.
• W2023956002 cites W1974108518 @default.
• W2023956002 cites W1974256738 @default.
• W2023956002 cites W1975366865 @default.
• W2023956002 cites W1980224053 @default.
• W2023956002 cites W1980590130 @default.
• W2023956002 cites W1990771263 @default.
• W2023956002 cites W1991115193 @default.
• W2023956002 cites W1992053982 @default.
• W2023956002 cites W1992912488 @default.
• W2023956002 cites W1993225916 @default.
• W2023956002 cites W1993857965 @default.
• W2023956002 cites W1994769697 @default.
• W2023956002 cites W1995067043 @default.
• W2023956002 cites W1996163526 @default.
• W2023956002 cites W1997732940 @default.
• W2023956002 cites W2001797583 @default.
• W2023956002 cites W2002541012 @default.
• W2023956002 cites W2005383842 @default.
• W2023956002 cites W2011000634 @default.
• W2023956002 cites W2013724724 @default.
• W2023956002 cites W2017916933 @default.
• W2023956002 cites W2021386768 @default.
• W2023956002 cites W2023408071 @default.
• W2023956002 cites W2024266959 @default.
• W2023956002 cites W2031762038 @default.
• W2023956002 cites W2050587934 @default.
• W2023956002 cites W2059857909 @default.
• W2023956002 cites W2061172474 @default.
• W2023956002 cites W2065616395 @default.
• W2023956002 cites W2071090857 @default.
• W2023956002 cites W2072997599 @default.
• W2023956002 cites W2080442644 @default.
• W2023956002 cites W2083492047 @default.
• W2023956002 cites W2089781384 @default.
• W2023956002 cites W2091246702 @default.
• W2023956002 cites W2095919110 @default.
• W2023956002 cites W2099353392 @default.
• W2023956002 cites W2100576228 @default.
• W2023956002 cites W2102123887 @default.
• W2023956002 cites W2103314990 @default.
• W2023956002 cites W2107925414 @default.
• W2023956002 cites W2114344041 @default.
• W2023956002 cites W2115441976 @default.
• W2023956002 cites W2118370975 @default.
• W2023956002 cites W2125967305 @default.
• W2023956002 cites W2126571188 @default.
• W2023956002 cites W2128498016 @default.
• W2023956002 cites W2131601689 @default.
• W2023956002 cites W2135241080 @default.
• W2023956002 cites W2138879960 @default.
• W2023956002 cites W2139159808 @default.
• W2023956002 cites W2144832496 @default.
• W2023956002 cites W2146610731 @default.
• W2023956002 cites W2148539277 @default.
• W2023956002 cites W2150402649 @default.
• W2023956002 cites W2161837912 @default.
• W2023956002 cites W2162514583 @default.
• W2023956002 cites W2163852287 @default.
• W2023956002 cites W2170841332 @default.
• W2023956002 cites W2259905666 @default.
• W2023956002 doi "https://doi.org/10.7326/0003-4819-152-10-201005180-00002" @default.
• W2023956002 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5468170" @default.
• W2023956002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20479027" @default.
• W2023956002 hasPublicationYear "2010" @default.
• W2023956002 type Work @default.
• W2023956002 sameAs 2023956002 @default.
• W2023956002 citedByCount "52" @default.
• W2023956002 countsByYear W20239560022012 @default.
• W2023956002 countsByYear W20239560022013 @default.
• W2023956002 countsByYear W20239560022014 @default.
• W2023956002 countsByYear W20239560022015 @default.
• W2023956002 countsByYear W20239560022016 @default.
• W2023956002 countsByYear W20239560022017 @default.
• W2023956002 countsByYear W20239560022018 @default.
• W2023956002 countsByYear W20239560022020 @default.
• W2023956002 countsByYear W20239560022021 @default.
• W2023956002 countsByYear W20239560022023 @default.
• W2023956002 crossrefType "journal-article" @default.
• W2023956002 hasAuthorship W2023956002A5001498977 @default.
• W2023956002 hasAuthorship W2023956002A5017288060 @default.
• W2023956002 hasAuthorship W2023956002A5063707394 @default.
• W2023956002 hasAuthorship W2023956002A5080965213 @default.
• W2023956002 hasBestOaLocation W20239560022 @default.
• W2023956002 hasConcept C112930515 @default.
• W2023956002 hasConcept C121608353 @default.

• next