FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023956656> ?p ?o ?g. }

• W2023956656 endingPage "507" @default.
• W2023956656 startingPage "507" @default.
• W2023956656 abstract "The incidence of nosocomial pneumonia involving methicillin-resistant Staphylococcus aureus strains (MRSA) is on the rise worldwide. For years, vancomycin has been used as the drug of choice in the treatment of MRSA infections and was recommended as such by clinical guidelines. There is growing evidence that vancomycin, despite low resistance rates is a suboptimal therapeutic option in critically ill patients, particularly in patients with pneumonia. Disadvantages of vancomycin are i) slow bactericide action, ii) poor penetration into pulmonary tissue, iii) the globally slowly increasing vancomycin MICs (creep) that result in increased clinical failure despite being susceptible according to defined break points and iv) nephrotoxicity. In contrast to other novel antibiotics with MRSA activity, Linezolid is currently approved for the treatment of nosocomial pneumonia in the USA and Europe. Several studies have compared vancomycin with linezolid for nosocomial pneumonia with conflicting results. This review compares both substances regarding pharmacodynamics, resistance, safety and clinical efficacy and discusses preliminary data of the ZEPHyR study. This study compared linezolid versus vancomycin in patients with proven MRSA pneumonia and was the largest trial ever conducted in this population." @default.
• W2023956656 created "2016-06-24" @default.
• W2023956656 creator A5019456706 @default.
• W2023956656 creator A5054664590 @default.
• W2023956656 creator A5059857876 @default.
• W2023956656 date "2010-01-01" @default.
• W2023956656 modified "2023-10-14" @default.
• W2023956656 title "Nosocomial methicillin-resistant staphylococcus aureus (MRSA) pneumonia: linezolid or vancomycin? - comparison of pharmacology and clinical efficacy" @default.
• W2023956656 cites W1525117555 @default.
• W2023956656 cites W1538461375 @default.
• W2023956656 cites W1541725315 @default.
• W2023956656 cites W1555403508 @default.
• W2023956656 cites W1867064160 @default.
• W2023956656 cites W1966573839 @default.
• W2023956656 cites W1969457805 @default.
• W2023956656 cites W1972922048 @default.
• W2023956656 cites W1981669571 @default.
• W2023956656 cites W1984745649 @default.
• W2023956656 cites W1985184557 @default.
• W2023956656 cites W1997275641 @default.
• W2023956656 cites W2001604291 @default.
• W2023956656 cites W2011569893 @default.
• W2023956656 cites W2013699996 @default.
• W2023956656 cites W2025471483 @default.
• W2023956656 cites W2028015105 @default.
• W2023956656 cites W2028378915 @default.
• W2023956656 cites W2032447526 @default.
• W2023956656 cites W2037724520 @default.
• W2023956656 cites W2038908775 @default.
• W2023956656 cites W2043132544 @default.
• W2023956656 cites W2045761133 @default.
• W2023956656 cites W2051834446 @default.
• W2023956656 cites W2056026648 @default.
• W2023956656 cites W2056829631 @default.
• W2023956656 cites W2061664070 @default.
• W2023956656 cites W2068037991 @default.
• W2023956656 cites W2070074382 @default.
• W2023956656 cites W2076664566 @default.
• W2023956656 cites W2077608176 @default.
• W2023956656 cites W2078561636 @default.
• W2023956656 cites W2079824217 @default.
• W2023956656 cites W2082441919 @default.
• W2023956656 cites W2091493523 @default.
• W2023956656 cites W2092196558 @default.
• W2023956656 cites W2094125922 @default.
• W2023956656 cites W2098013607 @default.
• W2023956656 cites W2103807926 @default.
• W2023956656 cites W2104609410 @default.
• W2023956656 cites W2106935542 @default.
• W2023956656 cites W2108525727 @default.
• W2023956656 cites W2108885025 @default.
• W2023956656 cites W2108934165 @default.
• W2023956656 cites W2111921516 @default.
• W2023956656 cites W2113662648 @default.
• W2023956656 cites W2116816874 @default.
• W2023956656 cites W2118897654 @default.
• W2023956656 cites W2120444754 @default.
• W2023956656 cites W2124628466 @default.
• W2023956656 cites W2125699736 @default.
• W2023956656 cites W2127755290 @default.
• W2023956656 cites W2128076923 @default.
• W2023956656 cites W2133120422 @default.
• W2023956656 cites W2135191756 @default.
• W2023956656 cites W2139049574 @default.
• W2023956656 cites W2144184683 @default.
• W2023956656 cites W2145851941 @default.
• W2023956656 cites W2148706534 @default.
• W2023956656 cites W2150388330 @default.
• W2023956656 cites W2155449333 @default.
• W2023956656 cites W2155666718 @default.
• W2023956656 cites W2156058032 @default.
• W2023956656 cites W2156283731 @default.
• W2023956656 cites W2158044259 @default.
• W2023956656 cites W2164475420 @default.
• W2023956656 cites W2166414974 @default.
• W2023956656 cites W2166425259 @default.
• W2023956656 cites W2171152889 @default.
• W2023956656 cites W2015655717 @default.
• W2023956656 doi "https://doi.org/10.1186/2047-783x-15-12-507" @default.
• W2023956656 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3352099" @default.
• W2023956656 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21163725" @default.
• W2023956656 hasPublicationYear "2010" @default.
• W2023956656 type Work @default.
• W2023956656 sameAs 2023956656 @default.
• W2023956656 citedByCount "42" @default.
• W2023956656 countsByYear W20239566562012 @default.
• W2023956656 countsByYear W20239566562013 @default.
• W2023956656 countsByYear W20239566562014 @default.
• W2023956656 countsByYear W20239566562015 @default.
• W2023956656 countsByYear W20239566562016 @default.
• W2023956656 countsByYear W20239566562017 @default.
• W2023956656 countsByYear W20239566562018 @default.
• W2023956656 countsByYear W20239566562019 @default.
• W2023956656 countsByYear W20239566562020 @default.
• W2023956656 countsByYear W20239566562021 @default.
• W2023956656 countsByYear W20239566562022 @default.
• W2023956656 crossrefType "journal-article" @default.
• W2023956656 hasAuthorship W2023956656A5019456706 @default.

• next