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- W2023961115 abstract "Many classes of non-coding RNAs (ncRNAs; including Y RNAs, vault RNAs, RNase P RNAs, and MRP RNAs, as well as a novel class recently discovered in Dictyostelium discoideum) can be characterized by a pattern of short but well-conserved sequence elements that are separated by poorly conserved regions of sometimes highly variable lengths. Local alignment algorithms such as BLAST are therefore ill-suited for the discovery of new homologs of such ncRNAs in genomic sequences. The Fragrep tool instead implements an efficient algorithm for detecting the pattern fragments that occur in a given order. For each pattern fragment, the mismatch tolerance and bounds on the length of the intervening sequences can be specified separately. Furthermore, matches can be ranked by a statistically well-motivated scoring scheme." @default.
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- W2023961115 date "2006-01-01" @default.
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- W2023961115 title "Fragrep: An Efficient Search Tool for Fragmented Patterns in Genomic Sequences" @default.
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- W2023961115 doi "https://doi.org/10.1016/s1672-0229(06)60017-x" @default.
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