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- W2023961213 abstract "We describe the transmission of an introduced minichromosome of brook trout (Salvelinus fontinalis) origin, carrying a pigmentation gene, through three generations in rainbow trout (Oncorhynchus mykiss). The minichromosome was originally introduced into gynogenetic albino rainbow trout using γ-irradiated brook trout sperm. In the third generation, the presence of the minichromosome was correlated with pigmentation. A brook trout specific interspersed repeat DNA sequence, Fok I, was also correlated with pigmentation in these individuals. This system, the first clearly documented example of induced chromosome mediated gene transfer at the organismal level, could have applications in studies of gene mapping, development, gene regulation, and chromosome function.Key words: gynogenesis, transgenic, trout, minichromosome, Oncorhynchus mykiss." @default.
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- W2023961213 date "1997-10-01" @default.
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- W2023961213 title "A minichromosome carrying a pigmentation gene and brook trout DNA sequences in transgenic rainbow trout" @default.
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- W2023961213 doi "https://doi.org/10.1139/g97-778" @default.
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