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• W2023961353 abstract "Levels of mRNAs coding for prodynorphin (Pro-Dyn) and proenkephalin (Pro-Enk) as well as the levels of immunoreactive (ir)-dynorphin1–17 (Dyn) and (ir)-Met-enkephalin (Met-Enk) were measured in the spinal cord of rats, 65 h following transection or injury of the spinal cord at the T6 spinal segment. Levels of both Pro-Dyn mRNA and of ir-Dyn were significantly increased between 60 and 150%, above control levels in the whole spinal cord, whereas those of Pro-Enk mRNA and of ir-Met-Enk remained unchanged. The increase in spinal levels of Pro-Dyn mRNA were highest in the areas close to the side of transection and indicate an involvement of the Pro-Dyn opioid system in the response to spinal injury and transection." @default.
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• W2023961353 date "1988-08-01" @default.
• W2023961353 modified "2023-09-27" @default.
• W2023961353 title "Prodynorphin gene expression in spinal cord is enhanced after traumatic injury in the rat" @default.
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• W2023961353 doi "https://doi.org/10.1016/0169-328x(88)90016-2" @default.
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