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• W2023969034 abstract "Synchronous HeLa S3 cultures were exposed to ultraviolet light at selected times in the generation cycle. Dose-survival curves show changes of both slope and extrapolation number. Sensitivity, measured as loss of colony-forming ability after doses of $70 {rm ergs} {rm mm}^{-2}$, increases late in G1, reaches a maximum in the middle of S, and decreases through the remainder of S and G2. The maximum occurs later than does the interphase maximum observed after X-irradiation with doses yielding about the same surviving fraction of cells. After doses up to $70 {rm ergs} {rm mm}^{-2}$, progression of cells from G1 to S or from G2 to mitosis is not blocked. Cells irradiated in G1 or S show a marked inhibition in the rate of incorporation of thymidine. The duration of DNA synthesis appears to be increased, resulting in a delay in cell division. Cells that die appear to do so largely before the first division after doses above $35 {rm ergs} {rm mm}^{-2}$. Incorporation of thymidine was detected in G1 a..." @default.
• W2023969034 created "2016-06-24" @default.
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• W2023969034 date "1967-10-01" @default.
• W2023969034 modified "2023-09-27" @default.
• W2023969034 title "Responses of Synchronous Populations of HeLa Cells to Ultraviolet Irradiation at Selected Stages of the Generation Cycle" @default.
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• W2023969034 doi "https://doi.org/10.2307/3572227" @default.
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