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- W2023969818 startingPage "849" @default.
- W2023969818 abstract "Increases in international travel and escalating drug resistance have resulted in a growing number of travelers at risk of contracting malaria. Drug resistance and intolerance to standard agents such as chloroquine, sulfadoxine/pyrimethamine and mefloquine has highlighted the need for new antimalarials. The recently licensed fixed combination of atovaquone and proguanil hydrochloride (Malarone™) is a promising new agent to prevent and treat Plasmodium falciparum malaria. Randomized controlled trials have shown that atovaquone/proguanil is well tolerated and efficacious for the prevention and treatment of drug-resistant P. falciparum malaria. Atovaquone/proguanil is active against the liver stage of P. falciparum malaria parasites and when used as a prophylactic agent it can be discontinued shortly after leaving malaria-endemic areas, offering a clear advantage for drug adherence." @default.
- W2023969818 created "2016-06-24" @default.
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- W2023969818 date "2005-12-01" @default.
- W2023969818 modified "2023-10-04" @default.
- W2023969818 title "Atovaquone/proguanil for the prophylaxis and treatment of malaria" @default.
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- W2023969818 doi "https://doi.org/10.1586/14787210.3.6.849" @default.
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