FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023973783> ?p ?o ?g. }

• W2023973783 endingPage "2452" @default.
• W2023973783 startingPage "2450" @default.
• W2023973783 abstract "Genetic determinants of longevity include the forkhead-related transcription factor DAF-16 in the worm Caenorhabditis elegans and the p66shc locus in mice. We demonstrate that p66shc regulates intracellular oxidant levels in mammalian cells and that hydrogen peroxide can negatively regulate forkhead activity. In p66shc-/- cells, the activity of the mammalian forkhead homolog FKHRL1 is increased and redox-dependent forkhead inactivation is reduced. In addition, expression of FKHRL1 results in an increase in both hydrogen peroxide scavenging and oxidative stress resistance. These results demonstrate an important functional relation between three distinct elements linked to aging: forkhead proteins, p66shc, and intracellular oxidants." @default.
• W2023973783 created "2016-06-24" @default.
• W2023973783 creator A5011179194 @default.
• W2023973783 creator A5085211904 @default.
• W2023973783 date "2002-03-29" @default.
• W2023973783 modified "2023-10-16" @default.
• W2023973783 title "Redox Regulation of Forkhead Proteins Through a<i>p66shc</i>-Dependent Signaling Pathway" @default.
• W2023973783 cites W1496668015 @default.
• W2023973783 cites W1625966995 @default.
• W2023973783 cites W1877188956 @default.
• W2023973783 cites W1972239225 @default.
• W2023973783 cites W1979147887 @default.
• W2023973783 cites W1991080848 @default.
• W2023973783 cites W1997052628 @default.
• W2023973783 cites W2002904952 @default.
• W2023973783 cites W2006796385 @default.
• W2023973783 cites W2007530728 @default.
• W2023973783 cites W2029936140 @default.
• W2023973783 cites W2043829280 @default.
• W2023973783 cites W2045012491 @default.
• W2023973783 cites W2070139659 @default.
• W2023973783 cites W2078804850 @default.
• W2023973783 cites W2084143461 @default.
• W2023973783 cites W2101861123 @default.
• W2023973783 cites W2106135888 @default.
• W2023973783 cites W2137035181 @default.
• W2023973783 cites W2165209574 @default.
• W2023973783 cites W2166525118 @default.
• W2023973783 cites W4245378753 @default.
• W2023973783 doi "https://doi.org/10.1126/science.1069004" @default.
• W2023973783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11884717" @default.
• W2023973783 hasPublicationYear "2002" @default.
• W2023973783 type Work @default.
• W2023973783 sameAs 2023973783 @default.
• W2023973783 citedByCount "780" @default.
• W2023973783 countsByYear W20239737832012 @default.
• W2023973783 countsByYear W20239737832013 @default.
• W2023973783 countsByYear W20239737832014 @default.
• W2023973783 countsByYear W20239737832015 @default.
• W2023973783 countsByYear W20239737832016 @default.
• W2023973783 countsByYear W20239737832017 @default.
• W2023973783 countsByYear W20239737832018 @default.
• W2023973783 countsByYear W20239737832019 @default.
• W2023973783 countsByYear W20239737832020 @default.
• W2023973783 countsByYear W20239737832021 @default.
• W2023973783 countsByYear W20239737832022 @default.
• W2023973783 countsByYear W20239737832023 @default.
• W2023973783 crossrefType "journal-article" @default.
• W2023973783 hasAuthorship W2023973783A5011179194 @default.
• W2023973783 hasAuthorship W2023973783A5085211904 @default.
• W2023973783 hasBestOaLocation W20239737831 @default.
• W2023973783 hasConcept C104317684 @default.
• W2023973783 hasConcept C127561419 @default.
• W2023973783 hasConcept C148397407 @default.
• W2023973783 hasConcept C181199279 @default.
• W2023973783 hasConcept C185592680 @default.
• W2023973783 hasConcept C2776151105 @default.
• W2023973783 hasConcept C2778944004 @default.
• W2023973783 hasConcept C2780391879 @default.
• W2023973783 hasConcept C2908554999 @default.
• W2023973783 hasConcept C533411734 @default.
• W2023973783 hasConcept C55493867 @default.
• W2023973783 hasConcept C75520062 @default.
• W2023973783 hasConcept C79879829 @default.
• W2023973783 hasConcept C86339819 @default.
• W2023973783 hasConcept C86803240 @default.
• W2023973783 hasConcept C95444343 @default.
• W2023973783 hasConceptScore W2023973783C104317684 @default.
• W2023973783 hasConceptScore W2023973783C127561419 @default.
• W2023973783 hasConceptScore W2023973783C148397407 @default.
• W2023973783 hasConceptScore W2023973783C181199279 @default.
• W2023973783 hasConceptScore W2023973783C185592680 @default.
• W2023973783 hasConceptScore W2023973783C2776151105 @default.
• W2023973783 hasConceptScore W2023973783C2778944004 @default.
• W2023973783 hasConceptScore W2023973783C2780391879 @default.
• W2023973783 hasConceptScore W2023973783C2908554999 @default.
• W2023973783 hasConceptScore W2023973783C533411734 @default.
• W2023973783 hasConceptScore W2023973783C55493867 @default.
• W2023973783 hasConceptScore W2023973783C75520062 @default.
• W2023973783 hasConceptScore W2023973783C79879829 @default.
• W2023973783 hasConceptScore W2023973783C86339819 @default.
• W2023973783 hasConceptScore W2023973783C86803240 @default.
• W2023973783 hasConceptScore W2023973783C95444343 @default.
• W2023973783 hasIssue "5564" @default.
• W2023973783 hasLocation W20239737831 @default.
• W2023973783 hasLocation W20239737832 @default.
• W2023973783 hasOpenAccess W2023973783 @default.
• W2023973783 hasPrimaryLocation W20239737831 @default.
• W2023973783 hasRelatedWork W1595882931 @default.
• W2023973783 hasRelatedWork W1986745001 @default.
• W2023973783 hasRelatedWork W2001283014 @default.
• W2023973783 hasRelatedWork W2003264741 @default.
• W2023973783 hasRelatedWork W2066045386 @default.
• W2023973783 hasRelatedWork W2081522807 @default.
• W2023973783 hasRelatedWork W2137195455 @default.
• W2023973783 hasRelatedWork W2150109371 @default.
• W2023973783 hasRelatedWork W2187869609 @default.
• W2023973783 hasRelatedWork W4249744465 @default.

• next