FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023983232> ?p ?o ?g. }

• W2023983232 endingPage "2374" @default.
• W2023983232 startingPage "2365" @default.
• W2023983232 abstract "Surgery does not cure more than 50% of “curable” rectal cancers. Local, regional, and disseminated cancers unremoved and untreated by surgery and other modalities account for this unrelenting mortality for the past 20 years. The results and promise of current investigations in multimodality approaches are discussed. Studies on lymph node histopathology seem to offer reliable prognostic significance in local or regionally confined disease. The use of adjuvant preoperative radiation foretells increased curability rates by decreasing the pathologic staging and local recurrence rates. Trials are under way potentiating the effects of radiation on tumor cells by combining it with various methods of hyperthermia or radiosensitizing compounds. Recent reports on the use of anticoagulation therapy at the time of surgery to prevent tumor cell implantation in fibrin networks indicate that this therapy is reasonable and worthy of more trial. The use of localized treatment in carefully selected patients is reviewed, including excision with electrocoagulation and contact x-ray therapy popularized in France by Papillon. Our early results of treatment by an interstitial iridium 192 rectal template afterloading technique are impressive. While chemotherapy for rectal cancer has, in general, been of no benefit, the combination of methyl-CCNU, vincristine and 5-FU seems to offer a reasonable response rate. The most exciting modality at present is immunotherapy. We believe that the adequate destruction of local and regional disease by radiation and surgery, the prevention of recurrent local and regional disease by radiation and surgery, the prevention of its local extension and implantation of metastases by anticoagulation and chemotherapy, with the stimulation of the hosts' immune response or prevention of immunosuppression by immunotherapy, are the indicated multimodalities of contemporary treatment." @default.
• W2023983232 created "2016-06-24" @default.
• W2023983232 creator A5064159894 @default.
• W2023983232 date "1977-11-01" @default.
• W2023983232 modified "2023-09-24" @default.
• W2023983232 title "Contemporary management of rectal cancer.An overview" @default.
• W2023983232 cites W1483023536 @default.
• W2023983232 cites W170242726 @default.
• W2023983232 cites W1756662394 @default.
• W2023983232 cites W1964448718 @default.
• W2023983232 cites W1969824532 @default.
• W2023983232 cites W1974632124 @default.
• W2023983232 cites W1977357440 @default.
• W2023983232 cites W1985697867 @default.
• W2023983232 cites W1987823805 @default.
• W2023983232 cites W1990841891 @default.
• W2023983232 cites W1992840688 @default.
• W2023983232 cites W1993115179 @default.
• W2023983232 cites W1998843338 @default.
• W2023983232 cites W2005748689 @default.
• W2023983232 cites W2012778426 @default.
• W2023983232 cites W2017463045 @default.
• W2023983232 cites W2019963761 @default.
• W2023983232 cites W2020938668 @default.
• W2023983232 cites W2024225059 @default.
• W2023983232 cites W2028868954 @default.
• W2023983232 cites W2037997948 @default.
• W2023983232 cites W2038836861 @default.
• W2023983232 cites W2043415771 @default.
• W2023983232 cites W2056412604 @default.
• W2023983232 cites W2057141714 @default.
• W2023983232 cites W2057579848 @default.
• W2023983232 cites W2060167886 @default.
• W2023983232 cites W2068897967 @default.
• W2023983232 cites W2069397741 @default.
• W2023983232 cites W2081621751 @default.
• W2023983232 cites W2090977835 @default.
• W2023983232 cites W2127718841 @default.
• W2023983232 cites W2150547487 @default.
• W2023983232 cites W2155580789 @default.
• W2023983232 cites W2196743588 @default.
• W2023983232 cites W2317384903 @default.
• W2023983232 cites W2323090795 @default.
• W2023983232 cites W2336404002 @default.
• W2023983232 cites W4230706052 @default.
• W2023983232 cites W4323236882 @default.
• W2023983232 doi "https://doi.org/10.1002/1097-0142(197711)40:5<2365::aid-cncr2820400553>3.0.co;2-7" @default.
• W2023983232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/336187" @default.
• W2023983232 hasPublicationYear "1977" @default.
• W2023983232 type Work @default.
• W2023983232 sameAs 2023983232 @default.
• W2023983232 citedByCount "5" @default.
• W2023983232 crossrefType "journal-article" @default.
• W2023983232 hasAuthorship W2023983232A5064159894 @default.
• W2023983232 hasBestOaLocation W20239832321 @default.
• W2023983232 hasConcept C121608353 @default.
• W2023983232 hasConcept C126322002 @default.
• W2023983232 hasConcept C126838900 @default.
• W2023983232 hasConcept C141071460 @default.
• W2023983232 hasConcept C2779134260 @default.
• W2023983232 hasConcept C509974204 @default.
• W2023983232 hasConcept C526805850 @default.
• W2023983232 hasConcept C71924100 @default.
• W2023983232 hasConceptScore W2023983232C121608353 @default.
• W2023983232 hasConceptScore W2023983232C126322002 @default.
• W2023983232 hasConceptScore W2023983232C126838900 @default.
• W2023983232 hasConceptScore W2023983232C141071460 @default.
• W2023983232 hasConceptScore W2023983232C2779134260 @default.
• W2023983232 hasConceptScore W2023983232C509974204 @default.
• W2023983232 hasConceptScore W2023983232C526805850 @default.
• W2023983232 hasConceptScore W2023983232C71924100 @default.
• W2023983232 hasIssue "5" @default.
• W2023983232 hasLocation W20239832321 @default.
• W2023983232 hasLocation W20239832322 @default.
• W2023983232 hasOpenAccess W2023983232 @default.
• W2023983232 hasPrimaryLocation W20239832321 @default.
• W2023983232 hasRelatedWork W2002120878 @default.
• W2023983232 hasRelatedWork W2003938723 @default.
• W2023983232 hasRelatedWork W2047967234 @default.
• W2023983232 hasRelatedWork W2118496982 @default.
• W2023983232 hasRelatedWork W2364998975 @default.
• W2023983232 hasRelatedWork W2369162477 @default.
• W2023983232 hasRelatedWork W2439875401 @default.
• W2023983232 hasRelatedWork W4238867864 @default.
• W2023983232 hasRelatedWork W2519357708 @default.
• W2023983232 hasRelatedWork W2525756941 @default.
• W2023983232 hasVolume "40" @default.
• W2023983232 isParatext "false" @default.
• W2023983232 isRetracted "false" @default.
• W2023983232 magId "2023983232" @default.
• W2023983232 workType "article" @default.