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• W2023983707 abstract "<i>Background:</i> We analyzed the outcome of patients with advanced unresectable pancreatic cancer treated in our department from 2001 to 2008. <i>Methods:</i> Of the 83 patients included in this study, 50 patients received single-agent treatment with gemcitabine (GEM), 9 patients GEM combined with radiotherapy (GEM+R) and 24 patients had best supportive care (BSC). We analyzed survival rates among the groups and risk factors for each group. <i>Results:</i> The 3-year survival rates were dismal: GEM group 2.9%, GEM+R group 0% and BSC group 0%. Significant prognostic factors of the study were: performance status (PS), response rate and decrease in the CA19-9 level. Significant prognostic factors by the Cox proportional hazard model were the albumin level prior to treatment, CA19-9 levels before treatment, decrease in CA19-9 and response rate. Albumin levels and the Glasgow Prognostic Score (GPS) were found to be factors affecting survival in the GEM group. <i>Conclusion:</i> In this series of patients with unresectable pancreatic cancer, good PS, decrease in CA19-9 after treatment and good GPS determined prior to treatment were independent prognostic factors for better overall survival." @default.
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• W2023983707 date "2010-01-01" @default.
• W2023983707 modified "2023-10-02" @default.
• W2023983707 title "The Glasgow Prognostic Score Is a Good Predictor of Treatment Outcome in Patients with Unresectable Pancreatic Cancer" @default.
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• W2023983707 doi "https://doi.org/10.1159/000321014" @default.
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