FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023984761> ?p ?o ?g. }

• W2023984761 endingPage "259" @default.
• W2023984761 startingPage "253" @default.
• W2023984761 abstract "Patients with any stage of small cell lung cancer were given low-dose interferon-alpha (IFN-alpha) from the first day of treatment as long as possible irrespective of changes in treatment dictated by disease progression. All patients received 6 cycles of the chemotherapy (CT): cisplatin 70 mg/m2 i.v. day 1 and etoposide 100 mg/m2 i.v. days 1, 2, 3 every 28 days. Seventy-eight patients were assigned to arm 1: CT alone, 75 patients to arm 2: CT + natural IFN-alpha (3 MU three times a week i.m.), and 66 patients to arm 3: CT + recombinant IFN alpha-2a (3 MU three times a week i.m.). There was no difference in median survival between the arms (10.2 months, 10.0 months, 10.1 months, respectively), p = 0.32. The 2-year survival rates were 15%, 3%, and 11%, respectively. Grade 3 and 4 leukopenia occurred more frequently in the IFN arms than in the CT alone arm and resulted in dose reductions. Antibodies occasionally developed to recombinant IFN. We conclude that IFN-alpha can be administered concomitantly with chemotherapy but is probably better kept for maintenance therapy so that optimal full doses of induction CT can be given." @default.
• W2023984761 created "2016-06-24" @default.
• W2023984761 creator A5000776327 @default.
• W2023984761 creator A5006944600 @default.
• W2023984761 creator A5013564776 @default.
• W2023984761 creator A5021255884 @default.
• W2023984761 creator A5034158111 @default.
• W2023984761 creator A5046282245 @default.
• W2023984761 creator A5052754967 @default.
• W2023984761 creator A5060849999 @default.
• W2023984761 creator A5063464975 @default.
• W2023984761 creator A5078211589 @default.
• W2023984761 creator A5081586416 @default.
• W2023984761 creator A5085930106 @default.
• W2023984761 creator A5086850466 @default.
• W2023984761 creator A5089173478 @default.
• W2023984761 creator A5090618504 @default.
• W2023984761 date "1999-03-01" @default.
• W2023984761 modified "2023-10-14" @default.
• W2023984761 title "Concomitant Chemotherapy and IFN-alpha for Small Cell Lung Cancer: A Randomized Multicenter Phase III Study" @default.
• W2023984761 cites W1963650660 @default.
• W2023984761 cites W2009055904 @default.
• W2023984761 cites W2034217772 @default.
• W2023984761 cites W2048370623 @default.
• W2023984761 cites W2157097596 @default.
• W2023984761 cites W2164569272 @default.
• W2023984761 cites W4239995323 @default.
• W2023984761 doi "https://doi.org/10.1089/107999099314180" @default.
• W2023984761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10213464" @default.
• W2023984761 hasPublicationYear "1999" @default.
• W2023984761 type Work @default.
• W2023984761 sameAs 2023984761 @default.
• W2023984761 citedByCount "28" @default.
• W2023984761 countsByYear W20239847612013 @default.
• W2023984761 countsByYear W20239847612015 @default.
• W2023984761 countsByYear W20239847612016 @default.
• W2023984761 countsByYear W20239847612018 @default.
• W2023984761 countsByYear W20239847612020 @default.
• W2023984761 countsByYear W20239847612021 @default.
• W2023984761 crossrefType "journal-article" @default.
• W2023984761 hasAuthorship W2023984761A5000776327 @default.
• W2023984761 hasAuthorship W2023984761A5006944600 @default.
• W2023984761 hasAuthorship W2023984761A5013564776 @default.
• W2023984761 hasAuthorship W2023984761A5021255884 @default.
• W2023984761 hasAuthorship W2023984761A5034158111 @default.
• W2023984761 hasAuthorship W2023984761A5046282245 @default.
• W2023984761 hasAuthorship W2023984761A5052754967 @default.
• W2023984761 hasAuthorship W2023984761A5060849999 @default.
• W2023984761 hasAuthorship W2023984761A5063464975 @default.
• W2023984761 hasAuthorship W2023984761A5078211589 @default.
• W2023984761 hasAuthorship W2023984761A5081586416 @default.
• W2023984761 hasAuthorship W2023984761A5085930106 @default.
• W2023984761 hasAuthorship W2023984761A5086850466 @default.
• W2023984761 hasAuthorship W2023984761A5089173478 @default.
• W2023984761 hasAuthorship W2023984761A5090618504 @default.
• W2023984761 hasConcept C121608353 @default.
• W2023984761 hasConcept C126322002 @default.
• W2023984761 hasConcept C141071460 @default.
• W2023984761 hasConcept C203014093 @default.
• W2023984761 hasConcept C2776178377 @default.
• W2023984761 hasConcept C2776256026 @default.
• W2023984761 hasConcept C2776694085 @default.
• W2023984761 hasConcept C2777701055 @default.
• W2023984761 hasConcept C2778119113 @default.
• W2023984761 hasConcept C2778239845 @default.
• W2023984761 hasConcept C2779384505 @default.
• W2023984761 hasConcept C2780873365 @default.
• W2023984761 hasConcept C2781228144 @default.
• W2023984761 hasConcept C2909179924 @default.
• W2023984761 hasConcept C2989005 @default.
• W2023984761 hasConcept C71924100 @default.
• W2023984761 hasConcept C90924648 @default.
• W2023984761 hasConceptScore W2023984761C121608353 @default.
• W2023984761 hasConceptScore W2023984761C126322002 @default.
• W2023984761 hasConceptScore W2023984761C141071460 @default.
• W2023984761 hasConceptScore W2023984761C203014093 @default.
• W2023984761 hasConceptScore W2023984761C2776178377 @default.
• W2023984761 hasConceptScore W2023984761C2776256026 @default.
• W2023984761 hasConceptScore W2023984761C2776694085 @default.
• W2023984761 hasConceptScore W2023984761C2777701055 @default.
• W2023984761 hasConceptScore W2023984761C2778119113 @default.
• W2023984761 hasConceptScore W2023984761C2778239845 @default.
• W2023984761 hasConceptScore W2023984761C2779384505 @default.
• W2023984761 hasConceptScore W2023984761C2780873365 @default.
• W2023984761 hasConceptScore W2023984761C2781228144 @default.
• W2023984761 hasConceptScore W2023984761C2909179924 @default.
• W2023984761 hasConceptScore W2023984761C2989005 @default.
• W2023984761 hasConceptScore W2023984761C71924100 @default.
• W2023984761 hasConceptScore W2023984761C90924648 @default.
• W2023984761 hasIssue "3" @default.
• W2023984761 hasLocation W20239847611 @default.
• W2023984761 hasLocation W20239847612 @default.
• W2023984761 hasOpenAccess W2023984761 @default.
• W2023984761 hasPrimaryLocation W20239847611 @default.
• W2023984761 hasRelatedWork W1749092708 @default.
• W2023984761 hasRelatedWork W1963650660 @default.
• W2023984761 hasRelatedWork W1980005853 @default.
• W2023984761 hasRelatedWork W2033860338 @default.

• next