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- W2023986232 endingPage "1946" @default.
- W2023986232 startingPage "1946" @default.
- W2023986232 abstract "We're back at square one, but knowing a lot more. With this wry admission, Robert A. Goepp, DDS, PhD, told<i>JAMA</i>MEDICAL NEWS of a second attempt, beginning soon, to assess the contraceptive efficacy of a custom-fitted valved cervical cap that he and obstetrician-gynecologist Uwe E. Freese, MD, invented (<i>JAMA</i>[MEDICAL NEWS] 1980;243:1617). An initial National Institutes of Health (NIH)-sponsored trial, begun in November 1981, was abruptly halted the following April, plagued by an excessive number of cap dislodgements and pregnancies. The cap's checkered history began one day in 1974 at the University of Chicago Pritzker School of Medicine, where both Goepp and Freese were faculty members. Freese was lamenting the deficiencies of the older, presized cervical caps, namely, dislodgement and malodor. The obvious solution, replied Goepp, to whom custom-fitting dental appliances was second nature, was to fashion an exactly fitting cervical cap with no cul-de-sacs where cervical mucus could" @default.
- W2023986232 created "2016-06-24" @default.
- W2023986232 creator A5049429120 @default.
- W2023986232 date "1983-10-21" @default.
- W2023986232 modified "2023-10-18" @default.
- W2023986232 title "Custom cervical cap reentering clinical trials" @default.
- W2023986232 doi "https://doi.org/10.1001/jama.1983.03340150004002" @default.
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