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- W2023987448 abstract "Membrane preparations containing essentially only the four polypeptides considered to constitute the acetylcholine receptor are purified from Torpedocalifornica electroplax. Treatment of these membranes with 2% (wv aqueous sodium cholate followed by removal of all insoluble matter results in a solubilized purified receptor preparation that can be reassociated with phospholipids during dialysis to remove the detergent. Such reconstituted receptor is shown to retain the capability of translocating 22Na+ across the membrane in response to carbamylcholine binding in a highly reproducible manner. The dose response for this effect is similar to that observed for the original electroplax membrane preparation and the carbamylcholine induced signal is completely blocked by α-bungarotoxin." @default.
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- W2023987448 date "1979-07-01" @default.
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- W2023987448 title "Carbamylcholine-induced rapid cation efflux from reconstituted membrane vesicles containing purified acetylcholine receptor" @default.
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- W2023987448 doi "https://doi.org/10.1016/0006-291x(79)90938-0" @default.
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