Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023987667> ?p ?o ?g. }
- W2023987667 endingPage "434" @default.
- W2023987667 startingPage "427" @default.
- W2023987667 abstract "Epithelial movements are key morphogenetic events in animal development. They are driven by multiple mechanisms, including signal-dependent changes in cytoskeletal organization and in cell adhesion. Such processes must be controlled precisely and coordinated to accurately sculpt the three-dimensional form of the developing organism. By observing the Drosophila epidermis during embryonic development using confocal time-lapse microscopy, we have investigated how signaling through the Jun-N-terminal kinase (JNK) pathway governs the tissue sheet movements that result in dorsal closure (DC). We find that JNK controls the polymerization of actin into a cable at the epidermal leading edge as previously suggested, as well as the joining (zipping) of the contralateral epithelial cell sheets. Here, we show that zipping is mediated by regulation of the integrins myospheroid and scab. Our data demonstrate that JNK signaling regulates a set of target genes that cooperate to facilitate epithelial movement and closure." @default.
- W2023987667 created "2016-06-24" @default.
- W2023987667 creator A5044917668 @default.
- W2023987667 creator A5060766913 @default.
- W2023987667 creator A5063179526 @default.
- W2023987667 creator A5067200001 @default.
- W2023987667 creator A5067580843 @default.
- W2023987667 creator A5076516874 @default.
- W2023987667 date "2005-11-29" @default.
- W2023987667 modified "2023-10-12" @default.
- W2023987667 title "JNK signaling coordinates integrin and actin functions during<i>Drosophila</i>embryogenesis" @default.
- W2023987667 cites W1938204331 @default.
- W2023987667 cites W1964084348 @default.
- W2023987667 cites W1965438893 @default.
- W2023987667 cites W1977831337 @default.
- W2023987667 cites W1979212686 @default.
- W2023987667 cites W1980157632 @default.
- W2023987667 cites W1981566818 @default.
- W2023987667 cites W1983436563 @default.
- W2023987667 cites W1983536745 @default.
- W2023987667 cites W1996850034 @default.
- W2023987667 cites W1997663906 @default.
- W2023987667 cites W2004127615 @default.
- W2023987667 cites W2014908429 @default.
- W2023987667 cites W2019065906 @default.
- W2023987667 cites W2036019393 @default.
- W2023987667 cites W2039862938 @default.
- W2023987667 cites W2061413580 @default.
- W2023987667 cites W2062089405 @default.
- W2023987667 cites W2063220206 @default.
- W2023987667 cites W2064832070 @default.
- W2023987667 cites W2075601071 @default.
- W2023987667 cites W2078968247 @default.
- W2023987667 cites W2087624263 @default.
- W2023987667 cites W2089613312 @default.
- W2023987667 cites W2093652869 @default.
- W2023987667 cites W2094735120 @default.
- W2023987667 cites W2094772268 @default.
- W2023987667 cites W2110367574 @default.
- W2023987667 cites W2110643873 @default.
- W2023987667 cites W2127352733 @default.
- W2023987667 cites W2131283226 @default.
- W2023987667 cites W2139172604 @default.
- W2023987667 cites W2146835460 @default.
- W2023987667 cites W2150858391 @default.
- W2023987667 cites W2156455641 @default.
- W2023987667 cites W2163174070 @default.
- W2023987667 cites W2164730800 @default.
- W2023987667 cites W2167047926 @default.
- W2023987667 cites W2183318287 @default.
- W2023987667 cites W2241971323 @default.
- W2023987667 cites W2260832199 @default.
- W2023987667 doi "https://doi.org/10.1002/dvdy.20649" @default.
- W2023987667 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16317725" @default.
- W2023987667 hasPublicationYear "2005" @default.
- W2023987667 type Work @default.
- W2023987667 sameAs 2023987667 @default.
- W2023987667 citedByCount "64" @default.
- W2023987667 countsByYear W20239876672012 @default.
- W2023987667 countsByYear W20239876672013 @default.
- W2023987667 countsByYear W20239876672014 @default.
- W2023987667 countsByYear W20239876672015 @default.
- W2023987667 countsByYear W20239876672016 @default.
- W2023987667 countsByYear W20239876672017 @default.
- W2023987667 countsByYear W20239876672018 @default.
- W2023987667 countsByYear W20239876672019 @default.
- W2023987667 countsByYear W20239876672021 @default.
- W2023987667 countsByYear W20239876672022 @default.
- W2023987667 countsByYear W20239876672023 @default.
- W2023987667 crossrefType "journal-article" @default.
- W2023987667 hasAuthorship W2023987667A5044917668 @default.
- W2023987667 hasAuthorship W2023987667A5060766913 @default.
- W2023987667 hasAuthorship W2023987667A5063179526 @default.
- W2023987667 hasAuthorship W2023987667A5067200001 @default.
- W2023987667 hasAuthorship W2023987667A5067580843 @default.
- W2023987667 hasAuthorship W2023987667A5076516874 @default.
- W2023987667 hasBestOaLocation W20239876671 @default.
- W2023987667 hasConcept C104317684 @default.
- W2023987667 hasConcept C105702510 @default.
- W2023987667 hasConcept C125705527 @default.
- W2023987667 hasConcept C142669718 @default.
- W2023987667 hasConcept C1491633281 @default.
- W2023987667 hasConcept C167290458 @default.
- W2023987667 hasConcept C195687474 @default.
- W2023987667 hasConcept C196843134 @default.
- W2023987667 hasConcept C2776458125 @default.
- W2023987667 hasConcept C2993400109 @default.
- W2023987667 hasConcept C40692019 @default.
- W2023987667 hasConcept C54355233 @default.
- W2023987667 hasConcept C62478195 @default.
- W2023987667 hasConcept C85789140 @default.
- W2023987667 hasConcept C86803240 @default.
- W2023987667 hasConcept C87073359 @default.
- W2023987667 hasConcept C95444343 @default.
- W2023987667 hasConceptScore W2023987667C104317684 @default.
- W2023987667 hasConceptScore W2023987667C105702510 @default.
- W2023987667 hasConceptScore W2023987667C125705527 @default.
- W2023987667 hasConceptScore W2023987667C142669718 @default.