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- W2023997032 abstract "HIV-1 involves three enzymes for its retroviral replication: reverse transcriptase, integrase and protease. Raltegravir belongs to the integrase strand transfer inhibitor family. Since the end of 2007, it was approved to use in treatment-experienced HIV-1 infected patients with multidrug resistance and treatment failure as a salvage therapy in recommended twice-daily dosage of 400 mg. However, on July 9th and on September 14th 2009, the FDA and the EMEA respectively, expanded the same dose approval to the use in treatment-naïve HIV-1 infected patients." @default.
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- W2023997032 date "2009-01-01" @default.
- W2023997032 modified "2023-10-16" @default.
- W2023997032 title "Raltegravir – a new agent in HIV-infected treatment-naive patients?" @default.
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- W2023997032 doi "https://doi.org/10.1016/s1730-1270(10)60085-9" @default.
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