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- W2024003574 abstract "The secretion of ATP from visualised varicosities on the surface of the mouse vas deferens was determined. Small diameter microelectrodes (about 6 μm and 20 μm) were placed over a set of 2 to 5 varicosities visualised with DiOC 2 (5) in order to record excitatory junctional currents (c.j.c.s′) arising from the evoked secretion of quanta. In high external calcium concentrations, [Ca 2+ ] 0 , the amplitude-frequency distribution of e.j.c.s′ was well described by binomial statistics in which binomial parameter n and the number of varicosities were approximately the same. Idazoxan (1 μM) had no effect on the e.j.c.s′ or the binomial parameters p and n . Suramin (100 μM) blocked the e.j.c.s′ as well as the spontaneous e.j.c.s′ (s.e.j.c.s′) in all cases. reducing n and p to zero. These results indicate that all varicosities secrete the transmitter blocked by suramin, presumably ATP." @default.
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- W2024003574 title "Evidence that each nerve varicosity on the surface of the mouse vas deferens secretes ATP" @default.
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- W2024003574 doi "https://doi.org/10.1016/0304-3940(93)90283-q" @default.
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