Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024010312> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2024010312 abstract "Generation of tryptophan-derived metabolites by indoleamine 2,3-dioxygenase (IDO) is a potent immunoregulatory mechanism in T cell responses. However, the mechanism remains unclear. We showed that 3-hydroxyanthranilic acid (3-HAA), the most potent metabolite, selectively induced apoptosis in activated T cells, but not in resting T cells. This was not associated with cell cycle arrest. We found that TRAIL expression was selectively induced in activated T cells by treatment of 3-HAA. Blockade of the TRAIL: DR4/DR5 pathway significantly inhibited 3-HAA-mediated T cell death. Our data suggest that TRAIL-induced apoptosis is involved in the mechanism of 3-HAA-mediated T cell death." @default.
- W2024010312 created "2016-06-24" @default.
- W2024010312 creator A5061511587 @default.
- W2024010312 date "2011-02-28" @default.
- W2024010312 modified "2023-09-25" @default.
- W2024010312 title "Tryptophan Metabolite 3-Hydroxyanthranilic Acid Augments TRAIL-Induced Apoptosis in Activated T Cells" @default.
- W2024010312 cites W1507810589 @default.
- W2024010312 cites W1607682771 @default.
- W2024010312 cites W1973251492 @default.
- W2024010312 cites W1975929837 @default.
- W2024010312 cites W1976751873 @default.
- W2024010312 cites W1981961784 @default.
- W2024010312 cites W1982737489 @default.
- W2024010312 cites W1985517826 @default.
- W2024010312 cites W1986222655 @default.
- W2024010312 cites W1988854695 @default.
- W2024010312 cites W2010378562 @default.
- W2024010312 cites W2015260577 @default.
- W2024010312 cites W2033333896 @default.
- W2024010312 cites W2057001364 @default.
- W2024010312 cites W2068432532 @default.
- W2024010312 cites W2072078248 @default.
- W2024010312 cites W2090410108 @default.
- W2024010312 cites W2123812720 @default.
- W2024010312 cites W2130988210 @default.
- W2024010312 cites W2140881278 @default.
- W2024010312 cites W2146914242 @default.
- W2024010312 cites W2160827995 @default.
- W2024010312 cites W2167897482 @default.
- W2024010312 cites W2170758122 @default.
- W2024010312 cites W75858226 @default.
- W2024010312 doi "https://doi.org/10.5352/jls.2011.21.2.316" @default.
- W2024010312 hasPublicationYear "2011" @default.
- W2024010312 type Work @default.
- W2024010312 sameAs 2024010312 @default.
- W2024010312 citedByCount "0" @default.
- W2024010312 crossrefType "journal-article" @default.
- W2024010312 hasAuthorship W2024010312A5061511587 @default.
- W2024010312 hasConcept C1491633281 @default.
- W2024010312 hasConcept C185592680 @default.
- W2024010312 hasConcept C190283241 @default.
- W2024010312 hasConcept C203014093 @default.
- W2024010312 hasConcept C2776090121 @default.
- W2024010312 hasConcept C2776706248 @default.
- W2024010312 hasConcept C2777477808 @default.
- W2024010312 hasConcept C31573885 @default.
- W2024010312 hasConcept C515207424 @default.
- W2024010312 hasConcept C55493867 @default.
- W2024010312 hasConcept C83478079 @default.
- W2024010312 hasConcept C86803240 @default.
- W2024010312 hasConcept C8891405 @default.
- W2024010312 hasConcept C95444343 @default.
- W2024010312 hasConceptScore W2024010312C1491633281 @default.
- W2024010312 hasConceptScore W2024010312C185592680 @default.
- W2024010312 hasConceptScore W2024010312C190283241 @default.
- W2024010312 hasConceptScore W2024010312C203014093 @default.
- W2024010312 hasConceptScore W2024010312C2776090121 @default.
- W2024010312 hasConceptScore W2024010312C2776706248 @default.
- W2024010312 hasConceptScore W2024010312C2777477808 @default.
- W2024010312 hasConceptScore W2024010312C31573885 @default.
- W2024010312 hasConceptScore W2024010312C515207424 @default.
- W2024010312 hasConceptScore W2024010312C55493867 @default.
- W2024010312 hasConceptScore W2024010312C83478079 @default.
- W2024010312 hasConceptScore W2024010312C86803240 @default.
- W2024010312 hasConceptScore W2024010312C8891405 @default.
- W2024010312 hasConceptScore W2024010312C95444343 @default.
- W2024010312 hasLocation W20240103121 @default.
- W2024010312 hasOpenAccess W2024010312 @default.
- W2024010312 hasPrimaryLocation W20240103121 @default.
- W2024010312 hasRelatedWork W142324782 @default.
- W2024010312 hasRelatedWork W1495607276 @default.
- W2024010312 hasRelatedWork W1598309391 @default.
- W2024010312 hasRelatedWork W1967280059 @default.
- W2024010312 hasRelatedWork W1977230260 @default.
- W2024010312 hasRelatedWork W1977328687 @default.
- W2024010312 hasRelatedWork W2002775741 @default.
- W2024010312 hasRelatedWork W2003237166 @default.
- W2024010312 hasRelatedWork W2008697475 @default.
- W2024010312 hasRelatedWork W2016642085 @default.
- W2024010312 hasRelatedWork W2033333896 @default.
- W2024010312 hasRelatedWork W2065318958 @default.
- W2024010312 hasRelatedWork W2069517682 @default.
- W2024010312 hasRelatedWork W2072078248 @default.
- W2024010312 hasRelatedWork W2082138658 @default.
- W2024010312 hasRelatedWork W2100626569 @default.
- W2024010312 hasRelatedWork W2138416076 @default.
- W2024010312 hasRelatedWork W2345512690 @default.
- W2024010312 hasRelatedWork W2569210752 @default.
- W2024010312 hasRelatedWork W829235025 @default.
- W2024010312 isParatext "false" @default.
- W2024010312 isRetracted "false" @default.
- W2024010312 magId "2024010312" @default.
- W2024010312 workType "article" @default.