Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024053150> ?p ?o ?g. }
- W2024053150 endingPage "1177" @default.
- W2024053150 startingPage "1163" @default.
- W2024053150 abstract "The existence and identification of adult renal stem cells is a controversial issue. In this study, renal stem cells were identified from cultures of clonal human nephrospheres. The cultured nephrospheres exhibited the activation of stem cell pathways and contained cells at different levels of maturation. In each nephrosphere the presence of 1.12–1.25 cells mirroring stem cell properties was calculated. The nephrosphere cells were able to generate three-dimensional tubular structures in 3D cultures and in vivo. In clonal human nephrospheres a PKHhigh phenotype was isolated using PKH26 epifluorescence, which can identify quiescent cells within the nephrospheres. The PKHhigh cells, capable of self-renewal and of generating a differentiated epithelial, endothelial and podocytic progeny, can also survive in vivo maintaining the undifferentiated status. The PKHhigh status, together with a CD133+/CD24− phenotype, identified a homogeneous cell population displaying in vitro self-renewal and multipotency capacity. The resident adult renal stem cell population isolated from nephrospheres can be used for the study of mechanisms that regulate self-renewal and differentiation in adult renal tissue as well as in renal pathological conditions." @default.
- W2024053150 created "2016-06-24" @default.
- W2024053150 creator A5002730356 @default.
- W2024053150 creator A5005158952 @default.
- W2024053150 creator A5014061027 @default.
- W2024053150 creator A5023554914 @default.
- W2024053150 creator A5024838965 @default.
- W2024053150 creator A5053525076 @default.
- W2024053150 creator A5055135834 @default.
- W2024053150 creator A5063336981 @default.
- W2024053150 creator A5064348968 @default.
- W2024053150 creator A5073480342 @default.
- W2024053150 creator A5081736345 @default.
- W2024053150 creator A5082488218 @default.
- W2024053150 date "2013-11-01" @default.
- W2024053150 modified "2023-10-03" @default.
- W2024053150 title "PKHhigh cells within clonal human nephrospheres provide a purified adult renal stem cell population" @default.
- W2024053150 cites W1835009115 @default.
- W2024053150 cites W1912639232 @default.
- W2024053150 cites W1969366572 @default.
- W2024053150 cites W1970604167 @default.
- W2024053150 cites W1984037615 @default.
- W2024053150 cites W1990315091 @default.
- W2024053150 cites W1992363390 @default.
- W2024053150 cites W1992495654 @default.
- W2024053150 cites W1999348847 @default.
- W2024053150 cites W2009130750 @default.
- W2024053150 cites W2020350080 @default.
- W2024053150 cites W2024518237 @default.
- W2024053150 cites W2025268465 @default.
- W2024053150 cites W2029969016 @default.
- W2024053150 cites W2045044865 @default.
- W2024053150 cites W2047475274 @default.
- W2024053150 cites W2049361962 @default.
- W2024053150 cites W2052204253 @default.
- W2024053150 cites W2063691541 @default.
- W2024053150 cites W2063933465 @default.
- W2024053150 cites W2066580758 @default.
- W2024053150 cites W2067146626 @default.
- W2024053150 cites W2073336166 @default.
- W2024053150 cites W2079356804 @default.
- W2024053150 cites W2085204161 @default.
- W2024053150 cites W2087922097 @default.
- W2024053150 cites W2097898298 @default.
- W2024053150 cites W2097942434 @default.
- W2024053150 cites W2111724542 @default.
- W2024053150 cites W2114062993 @default.
- W2024053150 cites W2119578188 @default.
- W2024053150 cites W2126968178 @default.
- W2024053150 cites W2127617517 @default.
- W2024053150 cites W2129781547 @default.
- W2024053150 cites W2133943800 @default.
- W2024053150 cites W2136825322 @default.
- W2024053150 cites W2140987848 @default.
- W2024053150 cites W2143372016 @default.
- W2024053150 cites W2148615664 @default.
- W2024053150 cites W2150393481 @default.
- W2024053150 cites W2153051750 @default.
- W2024053150 cites W2157010562 @default.
- W2024053150 cites W2167220389 @default.
- W2024053150 cites W2322564967 @default.
- W2024053150 doi "https://doi.org/10.1016/j.scr.2013.08.004" @default.
- W2024053150 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24012544" @default.
- W2024053150 hasPublicationYear "2013" @default.
- W2024053150 type Work @default.
- W2024053150 sameAs 2024053150 @default.
- W2024053150 citedByCount "29" @default.
- W2024053150 countsByYear W20240531502014 @default.
- W2024053150 countsByYear W20240531502015 @default.
- W2024053150 countsByYear W20240531502016 @default.
- W2024053150 countsByYear W20240531502017 @default.
- W2024053150 countsByYear W20240531502018 @default.
- W2024053150 countsByYear W20240531502019 @default.
- W2024053150 countsByYear W20240531502020 @default.
- W2024053150 countsByYear W20240531502021 @default.
- W2024053150 countsByYear W20240531502022 @default.
- W2024053150 countsByYear W20240531502023 @default.
- W2024053150 crossrefType "journal-article" @default.
- W2024053150 hasAuthorship W2024053150A5002730356 @default.
- W2024053150 hasAuthorship W2024053150A5005158952 @default.
- W2024053150 hasAuthorship W2024053150A5014061027 @default.
- W2024053150 hasAuthorship W2024053150A5023554914 @default.
- W2024053150 hasAuthorship W2024053150A5024838965 @default.
- W2024053150 hasAuthorship W2024053150A5053525076 @default.
- W2024053150 hasAuthorship W2024053150A5055135834 @default.
- W2024053150 hasAuthorship W2024053150A5063336981 @default.
- W2024053150 hasAuthorship W2024053150A5064348968 @default.
- W2024053150 hasAuthorship W2024053150A5073480342 @default.
- W2024053150 hasAuthorship W2024053150A5081736345 @default.
- W2024053150 hasAuthorship W2024053150A5082488218 @default.
- W2024053150 hasConcept C104317684 @default.
- W2024053150 hasConcept C123012128 @default.
- W2024053150 hasConcept C136302470 @default.
- W2024053150 hasConcept C144024400 @default.
- W2024053150 hasConcept C148738053 @default.
- W2024053150 hasConcept C149923435 @default.
- W2024053150 hasConcept C202751555 @default.
- W2024053150 hasConcept C203014093 @default.