Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024057404> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2024057404 endingPage "11" @default.
- W2024057404 startingPage "807" @default.
- W2024057404 abstract "Thiorphan, a potent inhibitor of enkephalinase (membrane metalloendopeptidase, atriopeptidase, EC 3.4.24.11) enhanced markedly (+214%) and prolonged the rise in plasma atrial natriuretic factor (ANF) immunoreactivity in anesthetized rats submitted to acute extracellular volume expansion obtained through i.v. injection of a Ringer's solution. These changes were accompanied by marked potentiations of the natriuretic and diuretic responses to the ANF-releasing stimulus, whereas kaliuresis was only slightly affected. Thiorphan also enhanced markedly the biphasic rise in urinary cyclic GMP excretion elicited by volume expansion. All these renal responses to volume expansion in thiorphan-treated rats were significantly reduced by pretreatment with anti-ANF antibodies, suggesting an involvement of the endogenous natriuretic hormone protected against degradation. However, pretreatment with antibradykinin antibodies led to qualitatively similar results, suggesting that the endogenous kinin-generating system in kidney may also participate in the responses to endogenous ANF and their potentiation by the peptidase inhibitor." @default.
- W2024057404 created "2016-06-24" @default.
- W2024057404 creator A5061119073 @default.
- W2024057404 date "1991-09-01" @default.
- W2024057404 modified "2023-09-23" @default.
- W2024057404 title "Thiorphan-induced natriuresis in volume-expanded rats: roles of endogenous atrial natriuretic factor and kinins." @default.
- W2024057404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1653839" @default.
- W2024057404 hasPublicationYear "1991" @default.
- W2024057404 type Work @default.
- W2024057404 sameAs 2024057404 @default.
- W2024057404 citedByCount "2" @default.
- W2024057404 countsByYear W20240574042018 @default.
- W2024057404 crossrefType "journal-article" @default.
- W2024057404 hasAuthorship W2024057404A5061119073 @default.
- W2024057404 hasConcept C104826730 @default.
- W2024057404 hasConcept C126322002 @default.
- W2024057404 hasConcept C134018914 @default.
- W2024057404 hasConcept C16613235 @default.
- W2024057404 hasConcept C170493617 @default.
- W2024057404 hasConcept C174459258 @default.
- W2024057404 hasConcept C181199279 @default.
- W2024057404 hasConcept C185592680 @default.
- W2024057404 hasConcept C195646399 @default.
- W2024057404 hasConcept C2113261 @default.
- W2024057404 hasConcept C2776246183 @default.
- W2024057404 hasConcept C2777803847 @default.
- W2024057404 hasConcept C2779547328 @default.
- W2024057404 hasConcept C2779591629 @default.
- W2024057404 hasConcept C2779918671 @default.
- W2024057404 hasConcept C2780011235 @default.
- W2024057404 hasConcept C2780091579 @default.
- W2024057404 hasConcept C2780268870 @default.
- W2024057404 hasConcept C2780919550 @default.
- W2024057404 hasConcept C2781063702 @default.
- W2024057404 hasConcept C2781231759 @default.
- W2024057404 hasConcept C2781372283 @default.
- W2024057404 hasConcept C28406088 @default.
- W2024057404 hasConcept C55493867 @default.
- W2024057404 hasConcept C71924100 @default.
- W2024057404 hasConcept C84393581 @default.
- W2024057404 hasConceptScore W2024057404C104826730 @default.
- W2024057404 hasConceptScore W2024057404C126322002 @default.
- W2024057404 hasConceptScore W2024057404C134018914 @default.
- W2024057404 hasConceptScore W2024057404C16613235 @default.
- W2024057404 hasConceptScore W2024057404C170493617 @default.
- W2024057404 hasConceptScore W2024057404C174459258 @default.
- W2024057404 hasConceptScore W2024057404C181199279 @default.
- W2024057404 hasConceptScore W2024057404C185592680 @default.
- W2024057404 hasConceptScore W2024057404C195646399 @default.
- W2024057404 hasConceptScore W2024057404C2113261 @default.
- W2024057404 hasConceptScore W2024057404C2776246183 @default.
- W2024057404 hasConceptScore W2024057404C2777803847 @default.
- W2024057404 hasConceptScore W2024057404C2779547328 @default.
- W2024057404 hasConceptScore W2024057404C2779591629 @default.
- W2024057404 hasConceptScore W2024057404C2779918671 @default.
- W2024057404 hasConceptScore W2024057404C2780011235 @default.
- W2024057404 hasConceptScore W2024057404C2780091579 @default.
- W2024057404 hasConceptScore W2024057404C2780268870 @default.
- W2024057404 hasConceptScore W2024057404C2780919550 @default.
- W2024057404 hasConceptScore W2024057404C2781063702 @default.
- W2024057404 hasConceptScore W2024057404C2781231759 @default.
- W2024057404 hasConceptScore W2024057404C2781372283 @default.
- W2024057404 hasConceptScore W2024057404C28406088 @default.
- W2024057404 hasConceptScore W2024057404C55493867 @default.
- W2024057404 hasConceptScore W2024057404C71924100 @default.
- W2024057404 hasConceptScore W2024057404C84393581 @default.
- W2024057404 hasIssue "3" @default.
- W2024057404 hasLocation W20240574041 @default.
- W2024057404 hasOpenAccess W2024057404 @default.
- W2024057404 hasPrimaryLocation W20240574041 @default.
- W2024057404 hasRelatedWork W1529925228 @default.
- W2024057404 hasRelatedWork W1830201437 @default.
- W2024057404 hasRelatedWork W1978201402 @default.
- W2024057404 hasRelatedWork W2024057404 @default.
- W2024057404 hasRelatedWork W2069587210 @default.
- W2024057404 hasRelatedWork W2075938400 @default.
- W2024057404 hasRelatedWork W2156834205 @default.
- W2024057404 hasRelatedWork W2283184147 @default.
- W2024057404 hasRelatedWork W2296513560 @default.
- W2024057404 hasRelatedWork W2325915750 @default.
- W2024057404 hasVolume "258" @default.
- W2024057404 isParatext "false" @default.
- W2024057404 isRetracted "false" @default.
- W2024057404 magId "2024057404" @default.
- W2024057404 workType "article" @default.