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- W2024071465 abstract "A new, potent hypocholesterolemic agent is produced by cultures of Aspergillus terreus. The isolation of the compound and its characterization as 4a, 5-dihydromevinolin containing a trans-fused octahydro-naphthalene system are described. Comparative data for dihydromevinolin and mevinolin in three biological assays are given: in vitro inhibition of HMG-CoA reductase, inhibition of sterol synthesis in cell cultures, and inhibition of cholesterol synthesis in vivo in rats." @default.
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- W2024071465 date "1981-01-01" @default.
- W2024071465 modified "2023-10-10" @default.
- W2024071465 title "Dihydromevinolin,a potent hypocholesterolemic metabolite produced by Aspergillus terreus." @default.
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- W2024071465 doi "https://doi.org/10.7164/antibiotics.34.507" @default.
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