Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024071751> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2024071751 endingPage "52" @default.
- W2024071751 startingPage "46" @default.
- W2024071751 abstract "Objective: To determine whether adding aggressive debridement to oral terbinafine for treating toenail onychomycosis impacts patient‐reported outcomes (PROs). Materials and methods: A total of 504 patients were randomized to receive 12 weeks of terbinafine 250 mg/day with or without debridement, with an additional 36‐week follow‐up. The OnyCOE‐tTM, a validated disease‐specific PRO questionnaire, was completed at baseline and weeks 6, 12, 24, and 48. It included six multi‐item scales (symptom frequency, symptom bothersomeness, appearance problems, physical activities problems, stigma, and treatment satisfaction), and one single‐item scale: overall problem. Longitudinal analysis of change was conducted to assess treatment effect. Repeated‐measures models adjusted for visit, age, sex, baseline scores, severity and duration of infection; treatment interactions were also tested. Results: Symptom frequency and treatment satisfaction significantly improved in the terbinafine + debridement group compared with terbinafine alone (p = 0.0395 and p = 0.0077, respectively). Age and sex were often significant explanatory variables, and further analysis of change scores at 12 weeks revealed that females treated with terbinafine + debridement reported significantly less improvement in the physical activities problems (p = 0.0021) and overall problem (p = 0.0112) scores. Conclusions: Aggressive debridement, when used as an adjunct therapy with oral terbinafine, improved treatment satisfaction and reduced symptom frequency. The observed sex differences warrant further investigation." @default.
- W2024071751 created "2016-06-24" @default.
- W2024071751 creator A5004154463 @default.
- W2024071751 creator A5046711811 @default.
- W2024071751 creator A5049478652 @default.
- W2024071751 creator A5058933500 @default.
- W2024071751 creator A5059918466 @default.
- W2024071751 creator A5078158480 @default.
- W2024071751 date "2007-01-01" @default.
- W2024071751 modified "2023-10-10" @default.
- W2024071751 title "The impact of aggressive debridement used as an adjunct therapy with terbinafine on perceptions of patients undergoing treatment for toenail onychomycosis" @default.
- W2024071751 cites W1982943090 @default.
- W2024071751 cites W2024951429 @default.
- W2024071751 cites W2031580084 @default.
- W2024071751 cites W2052595254 @default.
- W2024071751 cites W2056220318 @default.
- W2024071751 cites W2062471827 @default.
- W2024071751 cites W2080314607 @default.
- W2024071751 cites W2084696188 @default.
- W2024071751 cites W2106242890 @default.
- W2024071751 cites W2146261437 @default.
- W2024071751 doi "https://doi.org/10.1080/09546630600965004" @default.
- W2024071751 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17373090" @default.
- W2024071751 hasPublicationYear "2007" @default.
- W2024071751 type Work @default.
- W2024071751 sameAs 2024071751 @default.
- W2024071751 citedByCount "25" @default.
- W2024071751 countsByYear W20240717512012 @default.
- W2024071751 countsByYear W20240717512013 @default.
- W2024071751 countsByYear W20240717512014 @default.
- W2024071751 countsByYear W20240717512016 @default.
- W2024071751 countsByYear W20240717512017 @default.
- W2024071751 countsByYear W20240717512018 @default.
- W2024071751 countsByYear W20240717512019 @default.
- W2024071751 countsByYear W20240717512020 @default.
- W2024071751 countsByYear W20240717512021 @default.
- W2024071751 countsByYear W20240717512022 @default.
- W2024071751 countsByYear W20240717512023 @default.
- W2024071751 crossrefType "journal-article" @default.
- W2024071751 hasAuthorship W2024071751A5004154463 @default.
- W2024071751 hasAuthorship W2024071751A5046711811 @default.
- W2024071751 hasAuthorship W2024071751A5049478652 @default.
- W2024071751 hasAuthorship W2024071751A5058933500 @default.
- W2024071751 hasAuthorship W2024071751A5059918466 @default.
- W2024071751 hasAuthorship W2024071751A5078158480 @default.
- W2024071751 hasConcept C126322002 @default.
- W2024071751 hasConcept C141071460 @default.
- W2024071751 hasConcept C16005928 @default.
- W2024071751 hasConcept C1862650 @default.
- W2024071751 hasConcept C2777071850 @default.
- W2024071751 hasConcept C2777438270 @default.
- W2024071751 hasConcept C2778236110 @default.
- W2024071751 hasConcept C2779548794 @default.
- W2024071751 hasConcept C500440147 @default.
- W2024071751 hasConcept C71924100 @default.
- W2024071751 hasConceptScore W2024071751C126322002 @default.
- W2024071751 hasConceptScore W2024071751C141071460 @default.
- W2024071751 hasConceptScore W2024071751C16005928 @default.
- W2024071751 hasConceptScore W2024071751C1862650 @default.
- W2024071751 hasConceptScore W2024071751C2777071850 @default.
- W2024071751 hasConceptScore W2024071751C2777438270 @default.
- W2024071751 hasConceptScore W2024071751C2778236110 @default.
- W2024071751 hasConceptScore W2024071751C2779548794 @default.
- W2024071751 hasConceptScore W2024071751C500440147 @default.
- W2024071751 hasConceptScore W2024071751C71924100 @default.
- W2024071751 hasIssue "1" @default.
- W2024071751 hasLocation W20240717511 @default.
- W2024071751 hasLocation W20240717512 @default.
- W2024071751 hasOpenAccess W2024071751 @default.
- W2024071751 hasPrimaryLocation W20240717511 @default.
- W2024071751 hasRelatedWork W111998303 @default.
- W2024071751 hasRelatedWork W1999072654 @default.
- W2024071751 hasRelatedWork W2003293898 @default.
- W2024071751 hasRelatedWork W2025842671 @default.
- W2024071751 hasRelatedWork W2048735574 @default.
- W2024071751 hasRelatedWork W2106348716 @default.
- W2024071751 hasRelatedWork W2115184474 @default.
- W2024071751 hasRelatedWork W2176475586 @default.
- W2024071751 hasRelatedWork W2356342213 @default.
- W2024071751 hasRelatedWork W3093636769 @default.
- W2024071751 hasVolume "18" @default.
- W2024071751 isParatext "false" @default.
- W2024071751 isRetracted "false" @default.
- W2024071751 magId "2024071751" @default.
- W2024071751 workType "article" @default.