Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024102923> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2024102923 endingPage "209" @default.
- W2024102923 startingPage "204" @default.
- W2024102923 abstract "3D-QSAR analysis of a set of 37 analogues of SCH 66336 (Sarasar) was performed by most widely used computational tool, molecular field analysis (MFA) to investigate the substitutional requirements for the favorable receptor-drug interaction and to derive a predictive model that may be used for the designing of a novel farnesyltransferase inhibitors (FTIs). Regression analysis was carried out using genetic partial least squares (G/PLS) method. A highly predictive and statistically significant model was generated. The predictive ability of the model developed was assessed using a test set of six compounds (r2pred as high as 0.791). The analyzed MFA model has demonstrated a good fit, having r2 value of 0.967 and cross-validated coefficient r2cv value as 0.921." @default.
- W2024102923 created "2016-06-24" @default.
- W2024102923 creator A5017416851 @default.
- W2024102923 creator A5024604731 @default.
- W2024102923 creator A5068786796 @default.
- W2024102923 date "2008-01-01" @default.
- W2024102923 modified "2023-09-25" @default.
- W2024102923 title "Exploring three-dimensional quantitative structural activity relationship (3D-QSAR) analysis of SCH 66336 (Sarasar) analogues of farnesyltransferase inhibitors" @default.
- W2024102923 cites W1977681703 @default.
- W2024102923 cites W1983030284 @default.
- W2024102923 cites W2008517160 @default.
- W2024102923 cites W2045926872 @default.
- W2024102923 cites W2052080593 @default.
- W2024102923 cites W2059431360 @default.
- W2024102923 cites W2063778447 @default.
- W2024102923 cites W2067599110 @default.
- W2024102923 cites W2069545903 @default.
- W2024102923 cites W2077973224 @default.
- W2024102923 cites W2085822586 @default.
- W2024102923 cites W2087661061 @default.
- W2024102923 cites W2140689524 @default.
- W2024102923 cites W2170350529 @default.
- W2024102923 cites W2176744910 @default.
- W2024102923 cites W2951256269 @default.
- W2024102923 doi "https://doi.org/10.1016/j.ejmech.2007.02.013" @default.
- W2024102923 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17442459" @default.
- W2024102923 hasPublicationYear "2008" @default.
- W2024102923 type Work @default.
- W2024102923 sameAs 2024102923 @default.
- W2024102923 citedByCount "20" @default.
- W2024102923 countsByYear W20241029232012 @default.
- W2024102923 countsByYear W20241029232013 @default.
- W2024102923 countsByYear W20241029232015 @default.
- W2024102923 countsByYear W20241029232019 @default.
- W2024102923 countsByYear W20241029232021 @default.
- W2024102923 countsByYear W20241029232023 @default.
- W2024102923 crossrefType "journal-article" @default.
- W2024102923 hasAuthorship W2024102923A5017416851 @default.
- W2024102923 hasAuthorship W2024102923A5024604731 @default.
- W2024102923 hasAuthorship W2024102923A5068786796 @default.
- W2024102923 hasConcept C105795698 @default.
- W2024102923 hasConcept C126322002 @default.
- W2024102923 hasConcept C164126121 @default.
- W2024102923 hasConcept C169903167 @default.
- W2024102923 hasConcept C178910836 @default.
- W2024102923 hasConcept C181199279 @default.
- W2024102923 hasConcept C185592680 @default.
- W2024102923 hasConcept C22354355 @default.
- W2024102923 hasConcept C2777827897 @default.
- W2024102923 hasConcept C2778396349 @default.
- W2024102923 hasConcept C3019719930 @default.
- W2024102923 hasConcept C33923547 @default.
- W2024102923 hasConcept C48921125 @default.
- W2024102923 hasConcept C55493867 @default.
- W2024102923 hasConcept C57790582 @default.
- W2024102923 hasConcept C71240020 @default.
- W2024102923 hasConcept C71924100 @default.
- W2024102923 hasConceptScore W2024102923C105795698 @default.
- W2024102923 hasConceptScore W2024102923C126322002 @default.
- W2024102923 hasConceptScore W2024102923C164126121 @default.
- W2024102923 hasConceptScore W2024102923C169903167 @default.
- W2024102923 hasConceptScore W2024102923C178910836 @default.
- W2024102923 hasConceptScore W2024102923C181199279 @default.
- W2024102923 hasConceptScore W2024102923C185592680 @default.
- W2024102923 hasConceptScore W2024102923C22354355 @default.
- W2024102923 hasConceptScore W2024102923C2777827897 @default.
- W2024102923 hasConceptScore W2024102923C2778396349 @default.
- W2024102923 hasConceptScore W2024102923C3019719930 @default.
- W2024102923 hasConceptScore W2024102923C33923547 @default.
- W2024102923 hasConceptScore W2024102923C48921125 @default.
- W2024102923 hasConceptScore W2024102923C55493867 @default.
- W2024102923 hasConceptScore W2024102923C57790582 @default.
- W2024102923 hasConceptScore W2024102923C71240020 @default.
- W2024102923 hasConceptScore W2024102923C71924100 @default.
- W2024102923 hasIssue "1" @default.
- W2024102923 hasLocation W20241029231 @default.
- W2024102923 hasLocation W20241029232 @default.
- W2024102923 hasOpenAccess W2024102923 @default.
- W2024102923 hasPrimaryLocation W20241029231 @default.
- W2024102923 hasRelatedWork W1568748669 @default.
- W2024102923 hasRelatedWork W1990242727 @default.
- W2024102923 hasRelatedWork W1993632340 @default.
- W2024102923 hasRelatedWork W2024102923 @default.
- W2024102923 hasRelatedWork W2055461258 @default.
- W2024102923 hasRelatedWork W2077512324 @default.
- W2024102923 hasRelatedWork W3100593444 @default.
- W2024102923 hasRelatedWork W2183679436 @default.
- W2024102923 hasRelatedWork W2591978170 @default.
- W2024102923 hasRelatedWork W2596068644 @default.
- W2024102923 hasVolume "43" @default.
- W2024102923 isParatext "false" @default.
- W2024102923 isRetracted "false" @default.
- W2024102923 magId "2024102923" @default.
- W2024102923 workType "article" @default.