Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024110462> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2024110462 endingPage "410" @default.
- W2024110462 startingPage "407" @default.
- W2024110462 abstract "The current survival sepsis guideline proposes the use of vasopressors and fluid resuscitation to maintain the mean arterial pressure (MAP) ≥ 65 mmHg. Titrating catecholamine infusion to achieve higher MAP has been demonstrated to improve tissue oxygenation, microcirculation, renal function and overall outcome of the patient in some studies and literature on actual hemodynamic goals is scarce. AIM: To study the influence of two MAP on tissue oxygenation and perfusion parameters in patients of septic shock on norepinephrine infusion. SUBJECT AND MATERIALS: Forty adult patients with the diagnosis of septic shock were enrolled. In all patients norepinephrine was titrated to first stabilize the MAP at 65 ± 5 mmHg (Set I), followed by MAP of 85 ± 5 mmHg (Set II). Heart rate (HR), Central venous oxygen saturation (SCVO2), Transcutaneous partial pressure of oxygen (PtcO2) by TCM 400/TINA (using miniature Clark electrode), Arterial partial pressure of oxygen(PaO2), PtO2/PaO2 ratio, Urine output and Serum Base deficit were recorded in each Set after 2 hrs of stabilization. RESULTS: There was a significant increase in transcutaneous partial pressure of oxygen PtcO2 (p tO2/PaO2 (p < 0.0001), ScvO2 (p < 0.0001), urine output (p < 0.006) on increasing the MAP from 65mmHg to 85mmHg. Serum base deficit also improved (p < 0.0001). CONCLUSION: Higher MAP with norepinephrine is associated with better perfusion, oxygenation parameters in patients with established septic shock. These findings suggest that there is improvement in tissue oxygenation parameters using escalating doses of norepinephrine to achieve higher MAP without inherent adverse effect" @default.
- W2024110462 created "2016-06-24" @default.
- W2024110462 creator A5002586323 @default.
- W2024110462 creator A5016703318 @default.
- W2024110462 creator A5022846634 @default.
- W2024110462 creator A5042292119 @default.
- W2024110462 creator A5057241659 @default.
- W2024110462 date "2012-01-01" @default.
- W2024110462 modified "2023-10-18" @default.
- W2024110462 title "Effect of Higher Mean Arterial Pressure with Norepinephrine on Tissue Oxygenation and Perfusion in Patients of Septic Shock" @default.
- W2024110462 cites W1964655784 @default.
- W2024110462 cites W1977495126 @default.
- W2024110462 cites W1983105216 @default.
- W2024110462 cites W2020772136 @default.
- W2024110462 cites W2030910315 @default.
- W2024110462 cites W2084640166 @default.
- W2024110462 cites W2098885024 @default.
- W2024110462 cites W2102676019 @default.
- W2024110462 cites W2128855592 @default.
- W2024110462 cites W2150408626 @default.
- W2024110462 cites W2339939199 @default.
- W2024110462 cites W2599527603 @default.
- W2024110462 cites W2768146862 @default.
- W2024110462 doi "https://doi.org/10.4236/ijcm.2012.35076" @default.
- W2024110462 hasPublicationYear "2012" @default.
- W2024110462 type Work @default.
- W2024110462 sameAs 2024110462 @default.
- W2024110462 citedByCount "0" @default.
- W2024110462 crossrefType "journal-article" @default.
- W2024110462 hasAuthorship W2024110462A5002586323 @default.
- W2024110462 hasAuthorship W2024110462A5016703318 @default.
- W2024110462 hasAuthorship W2024110462A5022846634 @default.
- W2024110462 hasAuthorship W2024110462A5042292119 @default.
- W2024110462 hasAuthorship W2024110462A5057241659 @default.
- W2024110462 hasBestOaLocation W20241104621 @default.
- W2024110462 hasConcept C126322002 @default.
- W2024110462 hasConcept C146957229 @default.
- W2024110462 hasConcept C164705383 @default.
- W2024110462 hasConcept C178853913 @default.
- W2024110462 hasConcept C2776452961 @default.
- W2024110462 hasConcept C2777628635 @default.
- W2024110462 hasConcept C2777953023 @default.
- W2024110462 hasConcept C2778165595 @default.
- W2024110462 hasConcept C2778384902 @default.
- W2024110462 hasConcept C2778514916 @default.
- W2024110462 hasConcept C2781300812 @default.
- W2024110462 hasConcept C35207712 @default.
- W2024110462 hasConcept C42219234 @default.
- W2024110462 hasConcept C513476851 @default.
- W2024110462 hasConcept C70289976 @default.
- W2024110462 hasConcept C71924100 @default.
- W2024110462 hasConcept C84393581 @default.
- W2024110462 hasConceptScore W2024110462C126322002 @default.
- W2024110462 hasConceptScore W2024110462C146957229 @default.
- W2024110462 hasConceptScore W2024110462C164705383 @default.
- W2024110462 hasConceptScore W2024110462C178853913 @default.
- W2024110462 hasConceptScore W2024110462C2776452961 @default.
- W2024110462 hasConceptScore W2024110462C2777628635 @default.
- W2024110462 hasConceptScore W2024110462C2777953023 @default.
- W2024110462 hasConceptScore W2024110462C2778165595 @default.
- W2024110462 hasConceptScore W2024110462C2778384902 @default.
- W2024110462 hasConceptScore W2024110462C2778514916 @default.
- W2024110462 hasConceptScore W2024110462C2781300812 @default.
- W2024110462 hasConceptScore W2024110462C35207712 @default.
- W2024110462 hasConceptScore W2024110462C42219234 @default.
- W2024110462 hasConceptScore W2024110462C513476851 @default.
- W2024110462 hasConceptScore W2024110462C70289976 @default.
- W2024110462 hasConceptScore W2024110462C71924100 @default.
- W2024110462 hasConceptScore W2024110462C84393581 @default.
- W2024110462 hasIssue "05" @default.
- W2024110462 hasLocation W20241104621 @default.
- W2024110462 hasOpenAccess W2024110462 @default.
- W2024110462 hasPrimaryLocation W20241104621 @default.
- W2024110462 hasRelatedWork W2055092429 @default.
- W2024110462 hasRelatedWork W2351324836 @default.
- W2024110462 hasRelatedWork W2371596879 @default.
- W2024110462 hasRelatedWork W2388504448 @default.
- W2024110462 hasRelatedWork W2928438358 @default.
- W2024110462 hasRelatedWork W2981974646 @default.
- W2024110462 hasRelatedWork W3028765396 @default.
- W2024110462 hasRelatedWork W3029888705 @default.
- W2024110462 hasRelatedWork W3159274407 @default.
- W2024110462 hasRelatedWork W4291001102 @default.
- W2024110462 hasVolume "03" @default.
- W2024110462 isParatext "false" @default.
- W2024110462 isRetracted "false" @default.
- W2024110462 magId "2024110462" @default.
- W2024110462 workType "article" @default.