FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024115454> ?p ?o ?g. }

• W2024115454 endingPage "739" @default.
• W2024115454 startingPage "733" @default.
• W2024115454 abstract "High on-treatment platelet reactivity (HTPR) is present in a substantial percentage of patients on chronic clopidogrel treatment and may have prognostic implications. Strategies to optimize platelet inhibition in such patients are not clear. We performed a prospective, single-center, single-blinded, investigator-initiated randomized, crossover study of platelet inhibition by prasugrel 10 mg/day versus high-dose 150 mg/day clopidogrel, with a 14 day treatment period, in 31 patients with HTPR (out of 99 screened, 31.3%) while on chronic (≥ 12 months) treatment with clopidogrel. All patients had stable coronary artery disease and 87.1% of them had a prior percutaneous coronary intervention. Platelet reactivity (PR) was assessed by the VerifyNow assay measured in platelet reactivity units (PRU). The primary end point of PR at the end of the two treatment periods was lower in patients receiving prasugrel compared with high dose clopidogrel ( least squares estimate 148.1, 95% CI 127.1-169.2 and 219.8, 95% CI 198.6-240.9 respectively, P < .001). The secondary end point of HTPR rate was lower for prasugrel compared with clopidogrel, 11.5% vs 46.3%, P = .003. Prasugrel appears more effective than double clopidogrel in inhibiting PR in patients with HTPR following chronic clopidogrel treatment." @default.
• W2024115454 created "2016-06-24" @default.
• W2024115454 creator A5005503597 @default.
• W2024115454 creator A5010166506 @default.
• W2024115454 creator A5016879313 @default.
• W2024115454 creator A5065817262 @default.
• W2024115454 creator A5075144255 @default.
• W2024115454 creator A5085972858 @default.
• W2024115454 creator A5088583326 @default.
• W2024115454 date "2011-10-01" @default.
• W2024115454 modified "2023-10-15" @default.
• W2024115454 title "Prasugrel overcomes high on-clopidogrel platelet reactivity in chronic coronary artery disease patients more effectively than high dose (150 mg) clopidogrel" @default.
• W2024115454 cites W104398217 @default.
• W2024115454 cites W119348236 @default.
• W2024115454 cites W1756335821 @default.
• W2024115454 cites W1968677865 @default.
• W2024115454 cites W1974655135 @default.
• W2024115454 cites W1976411568 @default.
• W2024115454 cites W1994351107 @default.
• W2024115454 cites W2048708470 @default.
• W2024115454 cites W2076482318 @default.
• W2024115454 cites W2090438280 @default.
• W2024115454 cites W2097137681 @default.
• W2024115454 cites W2104595603 @default.
• W2024115454 cites W2104599604 @default.
• W2024115454 cites W2104969665 @default.
• W2024115454 cites W2108257482 @default.
• W2024115454 cites W2110897264 @default.
• W2024115454 cites W2128228188 @default.
• W2024115454 cites W2129507256 @default.
• W2024115454 cites W2147746835 @default.
• W2024115454 cites W2150086052 @default.
• W2024115454 cites W2152823642 @default.
• W2024115454 cites W2157833432 @default.
• W2024115454 cites W2165637474 @default.
• W2024115454 cites W2170312517 @default.
• W2024115454 cites W2887768525 @default.
• W2024115454 cites W67811773 @default.
• W2024115454 doi "https://doi.org/10.1016/j.ahj.2011.07.026" @default.
• W2024115454 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21982667" @default.
• W2024115454 hasPublicationYear "2011" @default.
• W2024115454 type Work @default.
• W2024115454 sameAs 2024115454 @default.
• W2024115454 citedByCount "58" @default.
• W2024115454 countsByYear W20241154542012 @default.
• W2024115454 countsByYear W20241154542013 @default.
• W2024115454 countsByYear W20241154542014 @default.
• W2024115454 countsByYear W20241154542015 @default.
• W2024115454 countsByYear W20241154542016 @default.
• W2024115454 countsByYear W20241154542017 @default.
• W2024115454 countsByYear W20241154542018 @default.
• W2024115454 countsByYear W20241154542019 @default.
• W2024115454 countsByYear W20241154542020 @default.
• W2024115454 countsByYear W20241154542023 @default.
• W2024115454 crossrefType "journal-article" @default.
• W2024115454 hasAuthorship W2024115454A5005503597 @default.
• W2024115454 hasAuthorship W2024115454A5010166506 @default.
• W2024115454 hasAuthorship W2024115454A5016879313 @default.
• W2024115454 hasAuthorship W2024115454A5065817262 @default.
• W2024115454 hasAuthorship W2024115454A5075144255 @default.
• W2024115454 hasAuthorship W2024115454A5085972858 @default.
• W2024115454 hasAuthorship W2024115454A5088583326 @default.
• W2024115454 hasConcept C126322002 @default.
• W2024115454 hasConcept C142724271 @default.
• W2024115454 hasConcept C164705383 @default.
• W2024115454 hasConcept C168563851 @default.
• W2024115454 hasConcept C203092338 @default.
• W2024115454 hasConcept C204787440 @default.
• W2024115454 hasConcept C27081682 @default.
• W2024115454 hasConcept C2777028646 @default.
• W2024115454 hasConcept C2777628954 @default.
• W2024115454 hasConcept C2777849778 @default.
• W2024115454 hasConcept C2778213512 @default.
• W2024115454 hasConcept C2780400711 @default.
• W2024115454 hasConcept C35294091 @default.
• W2024115454 hasConcept C49059817 @default.
• W2024115454 hasConcept C500558357 @default.
• W2024115454 hasConcept C71924100 @default.
• W2024115454 hasConcept C87813604 @default.
• W2024115454 hasConcept C89560881 @default.
• W2024115454 hasConceptScore W2024115454C126322002 @default.
• W2024115454 hasConceptScore W2024115454C142724271 @default.
• W2024115454 hasConceptScore W2024115454C164705383 @default.
• W2024115454 hasConceptScore W2024115454C168563851 @default.
• W2024115454 hasConceptScore W2024115454C203092338 @default.
• W2024115454 hasConceptScore W2024115454C204787440 @default.
• W2024115454 hasConceptScore W2024115454C27081682 @default.
• W2024115454 hasConceptScore W2024115454C2777028646 @default.
• W2024115454 hasConceptScore W2024115454C2777628954 @default.
• W2024115454 hasConceptScore W2024115454C2777849778 @default.
• W2024115454 hasConceptScore W2024115454C2778213512 @default.
• W2024115454 hasConceptScore W2024115454C2780400711 @default.
• W2024115454 hasConceptScore W2024115454C35294091 @default.
• W2024115454 hasConceptScore W2024115454C49059817 @default.
• W2024115454 hasConceptScore W2024115454C500558357 @default.
• W2024115454 hasConceptScore W2024115454C71924100 @default.
• W2024115454 hasConceptScore W2024115454C87813604 @default.
• W2024115454 hasConceptScore W2024115454C89560881 @default.

• next