FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024131694> ?p ?o ?g. }

• W2024131694 endingPage "642" @default.
• W2024131694 startingPage "639" @default.
• W2024131694 abstract "The carboxyl-terminal domain (BRCT) of the Breast Cancer Gene 1 (BRCA1) protein is an evolutionarily conserved module that exists in a large number of proteins from prokaryotes to eukaryotes. Although most BRCT domain–containing proteins participate in DNA-damage checkpoint or DNA-repair pathways, or both, the function of the BRCT domain is not fully understood. We show that the BRCA1 BRCT domain directly interacts with phosphorylated BRCA1-Associated Carboxyl-terminal Helicase (BACH1). This specific interaction between BRCA1 and phosphorylated BACH1 is cell cycle regulated and is required for DNA damage–induced checkpoint control during the transition from G 2 to M phase of the cell cycle. Further, we show that two other BRCT domains interact with their respective physiological partners in a phosphorylation-dependent manner. Thirteen additional BRCT domains also preferentially bind phospho-peptides rather than nonphosphorylated control peptides. These data imply that the BRCT domain is a phospho-protein binding domain involved in cell cycle control." @default.
• W2024131694 created "2016-06-24" @default.
• W2024131694 creator A5029892501 @default.
• W2024131694 creator A5042247081 @default.
• W2024131694 creator A5069046588 @default.
• W2024131694 creator A5082370575 @default.
• W2024131694 creator A5090845818 @default.
• W2024131694 date "2003-10-24" @default.
• W2024131694 modified "2023-10-10" @default.
• W2024131694 title "The BRCT Domain Is a Phospho-Protein Binding Domain" @default.
• W2024131694 cites W1768635289 @default.
• W2024131694 cites W1934253652 @default.
• W2024131694 cites W1969150779 @default.
• W2024131694 cites W2044409894 @default.
• W2024131694 cites W2052424743 @default.
• W2024131694 cites W2060107244 @default.
• W2024131694 cites W2068176376 @default.
• W2024131694 cites W2088179903 @default.
• W2024131694 cites W2104864755 @default.
• W2024131694 cites W2106976977 @default.
• W2024131694 cites W2109173575 @default.
• W2024131694 cites W2144401377 @default.
• W2024131694 cites W2163784018 @default.
• W2024131694 cites W2168225429 @default.
• W2024131694 doi "https://doi.org/10.1126/science.1088753" @default.
• W2024131694 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14576433" @default.
• W2024131694 hasPublicationYear "2003" @default.
• W2024131694 type Work @default.
• W2024131694 sameAs 2024131694 @default.
• W2024131694 citedByCount "754" @default.
• W2024131694 countsByYear W20241316942012 @default.
• W2024131694 countsByYear W20241316942013 @default.
• W2024131694 countsByYear W20241316942014 @default.
• W2024131694 countsByYear W20241316942015 @default.
• W2024131694 countsByYear W20241316942016 @default.
• W2024131694 countsByYear W20241316942017 @default.
• W2024131694 countsByYear W20241316942018 @default.
• W2024131694 countsByYear W20241316942019 @default.
• W2024131694 countsByYear W20241316942020 @default.
• W2024131694 countsByYear W20241316942021 @default.
• W2024131694 countsByYear W20241316942022 @default.
• W2024131694 countsByYear W20241316942023 @default.
• W2024131694 crossrefType "journal-article" @default.
• W2024131694 hasAuthorship W2024131694A5029892501 @default.
• W2024131694 hasAuthorship W2024131694A5042247081 @default.
• W2024131694 hasAuthorship W2024131694A5069046588 @default.
• W2024131694 hasAuthorship W2024131694A5082370575 @default.
• W2024131694 hasAuthorship W2024131694A5090845818 @default.
• W2024131694 hasConcept C104317684 @default.
• W2024131694 hasConcept C105696609 @default.
• W2024131694 hasConcept C11960822 @default.
• W2024131694 hasConcept C134935766 @default.
• W2024131694 hasConcept C143425029 @default.
• W2024131694 hasConcept C144292202 @default.
• W2024131694 hasConcept C161223559 @default.
• W2024131694 hasConcept C29537977 @default.
• W2024131694 hasConcept C5179208 @default.
• W2024131694 hasConcept C54086632 @default.
• W2024131694 hasConcept C54355233 @default.
• W2024131694 hasConcept C552990157 @default.
• W2024131694 hasConcept C67705224 @default.
• W2024131694 hasConcept C86339819 @default.
• W2024131694 hasConcept C86803240 @default.
• W2024131694 hasConcept C94966510 @default.
• W2024131694 hasConcept C95444343 @default.
• W2024131694 hasConceptScore W2024131694C104317684 @default.
• W2024131694 hasConceptScore W2024131694C105696609 @default.
• W2024131694 hasConceptScore W2024131694C11960822 @default.
• W2024131694 hasConceptScore W2024131694C134935766 @default.
• W2024131694 hasConceptScore W2024131694C143425029 @default.
• W2024131694 hasConceptScore W2024131694C144292202 @default.
• W2024131694 hasConceptScore W2024131694C161223559 @default.
• W2024131694 hasConceptScore W2024131694C29537977 @default.
• W2024131694 hasConceptScore W2024131694C5179208 @default.
• W2024131694 hasConceptScore W2024131694C54086632 @default.
• W2024131694 hasConceptScore W2024131694C54355233 @default.
• W2024131694 hasConceptScore W2024131694C552990157 @default.
• W2024131694 hasConceptScore W2024131694C67705224 @default.
• W2024131694 hasConceptScore W2024131694C86339819 @default.
• W2024131694 hasConceptScore W2024131694C86803240 @default.
• W2024131694 hasConceptScore W2024131694C94966510 @default.
• W2024131694 hasConceptScore W2024131694C95444343 @default.
• W2024131694 hasIssue "5645" @default.
• W2024131694 hasLocation W20241316941 @default.
• W2024131694 hasLocation W20241316942 @default.
• W2024131694 hasOpenAccess W2024131694 @default.
• W2024131694 hasPrimaryLocation W20241316941 @default.
• W2024131694 hasRelatedWork W1996366132 @default.
• W2024131694 hasRelatedWork W2029878748 @default.
• W2024131694 hasRelatedWork W2043916245 @default.
• W2024131694 hasRelatedWork W2093814864 @default.
• W2024131694 hasRelatedWork W2111510333 @default.
• W2024131694 hasRelatedWork W2139564764 @default.
• W2024131694 hasRelatedWork W2141022069 @default.
• W2024131694 hasRelatedWork W2316582027 @default.
• W2024131694 hasRelatedWork W2329294870 @default.
• W2024131694 hasRelatedWork W2176595488 @default.
• W2024131694 hasVolume "302" @default.

• next