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- W2024134846 abstract "Schizophrenia and mania have a number of symptoms and epidemiological characteristics in common, and both respond to dopamine blockade. Family, twin and molecular genetic studies suggest that the reason for these similarities may be that the two conditions share certain susceptibility genes. On the other hand, individuals with schizophrenia have more obvious brain structural and neuropsychological abnormalities than those with bipolar disorder; and pre-schizophrenic children are characterised by cognitive and neuromotor impairments, which are not shared by children who later develop bipolar disorder. Furthermore, the risk-increasing effect of obstetric complications has been demonstrated for schizophrenia but not for bipolar disorder. Perinatal complications such as hypoxia are known to result in smaller volume of the amygdala and hippocampus, which have been frequently reported to be reduced in schizophrenia; familial predisposition to schizophrenia is also associated with decreased volume of these structures. We suggest a model to explain the similarities and differences between the disorders and propose that, on a background of shared genetic predisposition to psychosis, schizophrenia, but not bipolar disorder, is subject to additional genes or early insults, which impair neurodevelopment, especially of the medial temporal lobe." @default.
- W2024134846 created "2016-06-24" @default.
- W2024134846 creator A5006791816 @default.
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- W2024134846 creator A5024831304 @default.
- W2024134846 creator A5029413844 @default.
- W2024134846 creator A5075718686 @default.
- W2024134846 date "2004-12-01" @default.
- W2024134846 modified "2023-10-14" @default.
- W2024134846 title "A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder" @default.
- W2024134846 cites W1577469161 @default.
- W2024134846 cites W1620401039 @default.
- W2024134846 cites W1964131466 @default.
- W2024134846 cites W1964667736 @default.
- W2024134846 cites W1968986034 @default.
- W2024134846 cites W1974214620 @default.
- W2024134846 cites W1983055116 @default.
- W2024134846 cites W1983164699 @default.
- W2024134846 cites W1983837040 @default.
- W2024134846 cites W1984017784 @default.
- W2024134846 cites W1988196101 @default.
- W2024134846 cites W1993068401 @default.
- W2024134846 cites W1996327177 @default.
- W2024134846 cites W2002851361 @default.
- W2024134846 cites W2004535146 @default.
- W2024134846 cites W2008896626 @default.
- W2024134846 cites W2009485462 @default.
- W2024134846 cites W2010402674 @default.
- W2024134846 cites W2013150436 @default.
- W2024134846 cites W2013336473 @default.
- W2024134846 cites W2014044116 @default.
- W2024134846 cites W2014462343 @default.
- W2024134846 cites W2014501270 @default.
- W2024134846 cites W2018851857 @default.
- W2024134846 cites W2018947064 @default.
- W2024134846 cites W2019813370 @default.
- W2024134846 cites W2020451388 @default.
- W2024134846 cites W2021085650 @default.
- W2024134846 cites W2026226974 @default.
- W2024134846 cites W2028693746 @default.
- W2024134846 cites W2032207621 @default.
- W2024134846 cites W2032650091 @default.
- W2024134846 cites W2032866243 @default.
- W2024134846 cites W2035172439 @default.
- W2024134846 cites W2036135177 @default.
- W2024134846 cites W2037914981 @default.
- W2024134846 cites W2038692754 @default.
- W2024134846 cites W2039629319 @default.
- W2024134846 cites W2043128631 @default.
- W2024134846 cites W2045378563 @default.
- W2024134846 cites W2045394963 @default.
- W2024134846 cites W2048409210 @default.
- W2024134846 cites W2053794651 @default.
- W2024134846 cites W2057453949 @default.
- W2024134846 cites W2058093057 @default.
- W2024134846 cites W2059431497 @default.
- W2024134846 cites W2061879617 @default.
- W2024134846 cites W2065931730 @default.
- W2024134846 cites W2069002800 @default.
- W2024134846 cites W2069378182 @default.
- W2024134846 cites W2071743179 @default.
- W2024134846 cites W2077989962 @default.
- W2024134846 cites W2079560049 @default.
- W2024134846 cites W2082647438 @default.
- W2024134846 cites W2084741079 @default.
- W2024134846 cites W2086377969 @default.
- W2024134846 cites W2087295904 @default.
- W2024134846 cites W2087621923 @default.
- W2024134846 cites W2089571727 @default.
- W2024134846 cites W2091615904 @default.
- W2024134846 cites W2092820864 @default.
- W2024134846 cites W2094383054 @default.
- W2024134846 cites W2094475773 @default.
- W2024134846 cites W2099550606 @default.
- W2024134846 cites W2102276141 @default.
- W2024134846 cites W2102583669 @default.
- W2024134846 cites W2104452175 @default.
- W2024134846 cites W2105774919 @default.
- W2024134846 cites W2106077828 @default.
- W2024134846 cites W2106488751 @default.
- W2024134846 cites W2115454208 @default.
- W2024134846 cites W2117950559 @default.
- W2024134846 cites W2121575582 @default.
- W2024134846 cites W2123565319 @default.
- W2024134846 cites W2124484391 @default.
- W2024134846 cites W2124524555 @default.
- W2024134846 cites W2126549748 @default.
- W2024134846 cites W2127054925 @default.
- W2024134846 cites W2127679160 @default.
- W2024134846 cites W2129937851 @default.
- W2024134846 cites W2130718539 @default.
- W2024134846 cites W2131014005 @default.
- W2024134846 cites W2132406375 @default.
- W2024134846 cites W2132908734 @default.
- W2024134846 cites W2136515852 @default.
- W2024134846 cites W2137984107 @default.
- W2024134846 cites W2138222426 @default.