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- W2024135514 abstract "Fetal anemia is linked to several conditions, such as red-cell alloimmunization or infections; in all these cases fetal hemoglobin levels determination is necessary for the management and eventually for a fetal transfusion. Until recently fetal hemoglobin levels have been evaluated with the use of cordocentesis. More recently Mari elaborated a new algorithm to calculate the fetal hemoglobin levels using the peak velocity of the middle cerebral artery with Doppler ultrasounds. Furthermore the DIAMOND Study group paper gives evidence that the Doppler ultrasonography can effectively replace cordocentesis to predict fetal anemia. We have recently performed a study to predict fetal anemia at term using the middle cerebral artery peak systolic velocity (MCA-PSV). We included only normal pregnancies (n = 40) in which a Cesarean section has been programmed because of previous Cesarean section or breech presentation. Immediately after birth the neonatal hemoglobin was obtained from the cord. Our data were significantly different from those expected using Mari's chart. We have calculated a regression curve fitting our data and the result (P < 0.001) is: Hb = 18.86 0.076 MCA-PSV Our work suggests that Mari's chart has limitations in the third trimester, possibly due to the different viscosity of fetal blood. In conclusion we would like to stress the usefulness of non-invasive method also in late pregnancy. The prediction of fetal anemia, in fact, may modify the management by the obstetricians." @default.
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- W2024135514 date "2007-09-21" @default.
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- W2024135514 title "P51.05: Non-invasive fetal hemoglobin evaluation near term" @default.
- W2024135514 doi "https://doi.org/10.1002/uog.5068" @default.
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