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- W2024138677 abstract "Rhabdomyolysis is characterized by breakdown of striated muscle due to a great number of causes. Acute kidney injury (AKI) is a common complication as a consequence of high concentrations of circulating myoglobin (Mb). The AKI degree can vary but often requires dialysis, a condition which drastically worsens the ICU stay and prognosis. Since Mb overconcentration represents the cause of AKI, one of the therapy's aims should be its removal to prevent further kidney damage and to allow faster renal recovery. Both intermittent hemodialysis and high-volume CVVHF are poorly effective in removing Mb, while small-protein leakage membranes seem to be promising in this setting. The aim of our study was therefore to measure efficacy of Mb removal of a new high cutoff membrane (EMIC2; Fresenius, cutoff value 40 kDa) for continuous renal replacement therapies (CRRT) in the ICU setting." @default.
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- W2024138677 date "2014-01-01" @default.
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- W2024138677 title "Myoglobin removal of small-protein leakage membrane (EMIC2) in patients in the ICU: a case series" @default.
- W2024138677 doi "https://doi.org/10.1186/cc13588" @default.
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