Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024139565> ?p ?o ?g. }
- W2024139565 endingPage "171" @default.
- W2024139565 startingPage "161" @default.
- W2024139565 abstract "Both photobiomodulation (PBM) and olfactory ensheathing cells (OECs) transplantation improve recovery following spinal cord injury. However, neither the combination of these two therapies nor the effect of light on OECs has been reported. The purpose of this study was to determine the effect of light on OEC activity in vitro.OECs were purified from adult rat olfactory bulbs and exposed to 810 nm light (150 mW; 0, 0.2, or 68 J/cm(2)). After 7-21 days in vitro, cells underwent immunocytochemistry or RNA extraction and RT-PCR.Analysis of immunolabeling revealed a significant decrease in fibronectin expression in the cultures receiving 68 J/cm(2). Analysis of gene expression revealed a significant (P < 0.05) increase in brain derived neurotrophic factor (BDNF), glial derived neurotrophic factor (GDNF), and collagen expression in the 0.2 J/cm(2) group in comparison to the non-irradiated and 68 J/cm(2) groups. OEC proliferation was also found to significantly increase in both light treated groups in comparison to the control group (P < 0.001).These results demonstrate that low and high dosages of PBM alter OEC activity, including upregulation of a number of neurotrophic growth factors and extracellular matrix proteins known to support neurite outgrowth. Therefore, the application of PBM in conjunction with OEC transplantation warrants consideration as a potential combination therapy for spinal cord injury." @default.
- W2024139565 created "2016-06-24" @default.
- W2024139565 creator A5023218393 @default.
- W2024139565 creator A5028219136 @default.
- W2024139565 creator A5051215581 @default.
- W2024139565 creator A5072579589 @default.
- W2024139565 creator A5075399406 @default.
- W2024139565 date "2005-01-01" @default.
- W2024139565 modified "2023-10-13" @default.
- W2024139565 title "Low power laser irradiation alters gene expression of olfactory ensheathing cells in vitro" @default.
- W2024139565 cites W1482140748 @default.
- W2024139565 cites W1570443809 @default.
- W2024139565 cites W1657897383 @default.
- W2024139565 cites W1973624424 @default.
- W2024139565 cites W1974004117 @default.
- W2024139565 cites W1974238971 @default.
- W2024139565 cites W1975890293 @default.
- W2024139565 cites W1976786944 @default.
- W2024139565 cites W1979338164 @default.
- W2024139565 cites W1984299380 @default.
- W2024139565 cites W1986451995 @default.
- W2024139565 cites W1988304756 @default.
- W2024139565 cites W1989249777 @default.
- W2024139565 cites W1999737434 @default.
- W2024139565 cites W2002502288 @default.
- W2024139565 cites W2003836543 @default.
- W2024139565 cites W2011351516 @default.
- W2024139565 cites W2012902876 @default.
- W2024139565 cites W2013270571 @default.
- W2024139565 cites W2013903451 @default.
- W2024139565 cites W2015208953 @default.
- W2024139565 cites W2021518416 @default.
- W2024139565 cites W2022310489 @default.
- W2024139565 cites W2027122523 @default.
- W2024139565 cites W2031270913 @default.
- W2024139565 cites W2031409761 @default.
- W2024139565 cites W2037865089 @default.
- W2024139565 cites W2040355927 @default.
- W2024139565 cites W2046954587 @default.
- W2024139565 cites W2047319747 @default.
- W2024139565 cites W2061305590 @default.
- W2024139565 cites W2061348706 @default.
- W2024139565 cites W2065798425 @default.
- W2024139565 cites W2066067872 @default.
- W2024139565 cites W2066844939 @default.
- W2024139565 cites W2069596318 @default.
- W2024139565 cites W2070712953 @default.
- W2024139565 cites W2071815922 @default.
- W2024139565 cites W2074184632 @default.
- W2024139565 cites W2087146423 @default.
- W2024139565 cites W2091282052 @default.
- W2024139565 cites W2094409158 @default.
- W2024139565 cites W2094491243 @default.
- W2024139565 cites W2110900455 @default.
- W2024139565 cites W2117603818 @default.
- W2024139565 cites W2124428807 @default.
- W2024139565 cites W2127221032 @default.
- W2024139565 cites W2127727844 @default.
- W2024139565 cites W2140440082 @default.
- W2024139565 cites W2143188831 @default.
- W2024139565 cites W2147788860 @default.
- W2024139565 cites W2148912320 @default.
- W2024139565 cites W2154827755 @default.
- W2024139565 cites W2160926967 @default.
- W2024139565 cites W2181012382 @default.
- W2024139565 cites W2321821953 @default.
- W2024139565 cites W2423554750 @default.
- W2024139565 cites W4241341155 @default.
- W2024139565 cites W4247668468 @default.
- W2024139565 doi "https://doi.org/10.1002/lsm.20202" @default.
- W2024139565 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16037971" @default.
- W2024139565 hasPublicationYear "2005" @default.
- W2024139565 type Work @default.
- W2024139565 sameAs 2024139565 @default.
- W2024139565 citedByCount "74" @default.
- W2024139565 countsByYear W20241395652012 @default.
- W2024139565 countsByYear W20241395652013 @default.
- W2024139565 countsByYear W20241395652014 @default.
- W2024139565 countsByYear W20241395652015 @default.
- W2024139565 countsByYear W20241395652016 @default.
- W2024139565 countsByYear W20241395652017 @default.
- W2024139565 countsByYear W20241395652018 @default.
- W2024139565 countsByYear W20241395652019 @default.
- W2024139565 countsByYear W20241395652020 @default.
- W2024139565 countsByYear W20241395652021 @default.
- W2024139565 countsByYear W20241395652022 @default.
- W2024139565 countsByYear W20241395652023 @default.
- W2024139565 crossrefType "journal-article" @default.
- W2024139565 hasAuthorship W2024139565A5023218393 @default.
- W2024139565 hasAuthorship W2024139565A5028219136 @default.
- W2024139565 hasAuthorship W2024139565A5051215581 @default.
- W2024139565 hasAuthorship W2024139565A5072579589 @default.
- W2024139565 hasAuthorship W2024139565A5075399406 @default.
- W2024139565 hasConcept C104317684 @default.
- W2024139565 hasConcept C113246987 @default.
- W2024139565 hasConcept C126322002 @default.
- W2024139565 hasConcept C127561419 @default.
- W2024139565 hasConcept C142724271 @default.